New Mouse Model for Muscular Dystrophy Studies Developed

A new mouse model for the study of Inclusion Body Myositis (IBM), a type of muscular dystrophy, has been developed by Dr. Ze’ev Ronai and a worldwide team of researchers.  The protein RNF5 is over-produced in the mice, resulting in extensive muscle damage similar to that seen in IBM patients.  The IBM mouse model will allow researchers to further study the mechanisms underlying development of the disease, as well as test potential new therapies.

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