[ZNF217 gene was detected in ovarian serous cystadenocarcinoma by fluorescence in situ hybridization]

[ZNF217 gene was detected in ovarian serous cystadenocarcinoma by fluorescence in situ hybridization] Research Abstract Details 

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[ZNF217 gene was detected in ovarian serous cystadenocarcinoma by fluorescence in situ hybridization] Abstract Text:

Mei Zhong,Jing Li,Yan-qing Ding,Lan-lin Song,Mei Zhong,Jing Li,Yan-qing Ding,Lan-lin Song,

OBJECTIVE: To investigate amplification of zinc finger protein 217 (ZNF217) gene in ovarian serous cystadenocarcinoma and its clinical significance. METHODS: Twenty three specimens of ovarian carcinoma, 10 specimens of ovarian benign tumors and 7 specimens of normal ovaries and two ovarian cancer cell lines, SKOV3 and HO-8910 were examined by fluorescence in situ hybridization (FISH). RESULTS: The amplification of ZNF217 was gained in 12 case of ovarian cancers, there was only 1 case in ovarian benign tumor and not amplication in normal ovary. CONCLUSION: The amplification of ZNF217 is associated with ovarian cancer. Oncogenes ZNF217 maybe play a role in cell differentiation and indicate poorer survival in patients with ovarian cancer.

[ZNF217 gene was detected in ovarian serous cystadenocarcinoma by fluorescence in situ hybridization] Publishing Authors By Initials

M Zhong,J Li,YQ Ding,LL Song,M Zhong,J Li,YQ Ding,LL Song,

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[ZNF217 gene was detected in ovarian serous cystadenocarcinoma by fluorescence in situ hybridization] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Zhonghua yi xue yi chuan xue za zhi = Zhonghua yix

VOLUME: 23

Page Numbers: 665-7

Journal Abbreviation: Zhonghua Yi Xue Yi Chuan Xue Z

ISSN: 1003-9406

DAY: 12

MONTH: Dec

YEAR: 2006

[ZNF217 gene was detected in ovarian serous cystadenocarcinoma by fluorescence in situ hybridization] Information

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LANGUAGE: chi

NlmUniqueID: 9425197

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AFFILIATION: Department of Gynecology and Obstetrics, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, 510515, P. R. China. zhongmei@fimmu.com

Country: China

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MEDLINETA: Zhonghua Yi Xue Yi Chuan Xue Z

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