Ziwi, the zebrafish homologue of the Drosophila piwi: co-localization with vasa at the embryonic genital ridge and gonad-specific expression in the adults.

Ziwi, the zebrafish homologue of the Drosophila piwi: co-localization with vasa at the embryonic genital ridge and gonad-specific expression in the adults. Research Abstract Details 

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Ziwi, the zebrafish homologue of the Drosophila piwi: co-localization with vasa at the embryonic genital ridge and gonad-specific expression in the adults. Abstract Text:

Cheong-Huat Tan,Thean-Chu Lee,Shyamal D Weeraratne,Vladimir Korzh,Tit-Meng Lim,Zhiyuan Gong,

PIWI regulates the proliferation and maintenance of germline stem cells in diverse organisms. The full-length 3.26 kb ziwi cDNA, the zebrafish homologue of piwi of Drosophila, encodes a putative protein of 858 amino acids. ZIWI is 65% homologous with the mouse and human PIWI, but only 38 and 33% with Caenorhabditis elegans and Drosophila PIWI, respectively. In adult zebrafish, ziwi is expressed exclusively in the gonads. In embryos and fry, its expression is detectable initially during segmentation and persisted for at least 4 weeks post hatching. During neurogenesis and organogenesis, its expression was detected in the CNS and fin buds. Starting from 24 hpf and later on, ziwi transcripts were found in the genital ridge.

Ziwi, the zebrafish homologue of the Drosophila piwi: co-localization with vasa at the embryonic genital ridge and gonad-specific expression in the adults. Publishing Authors By Initials

CH Tan,TC Lee,SD Weeraratne,V Korzh,TM Lim,Z Gong,

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Ziwi, the zebrafish homologue of the Drosophila piwi: co-localization with vasa at the embryonic genital ridge and gonad-specific expression in the adults. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Mechanisms of development

VOLUME: 119 Suppl 1

Page Numbers: S221-4

Journal Abbreviation: Mech. Dev.

ISSN: 0925-4773

DAY: 30

MONTH: Dec

YEAR: 2002

Ziwi, the zebrafish homologue of the Drosophila piwi: co-localization with vasa at the embryonic genital ridge and gonad-specific expression in the adults. Information

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LANGUAGE: eng

NlmUniqueID: 9101218

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AFFILIATION: Department of Biological Sciences, National University of Singapore, Singapore. dbstanch@nus.edu.sg

Country: Ireland

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MEDLINETA: Mech Dev

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