Yeast gene which suppresses the defect in protein export of a secY mutant of E. coli.

Yeast gene which suppresses the defect in protein export of a secY mutant of E. coli. Research Abstract Details 

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Yeast gene which suppresses the defect in protein export of a secY mutant of E. coli. Abstract Text:

M Sakaguchi,C Ueguchi,K Ito,T Omura,

To find factors participating in protein translocation in yeast, we screened a yeast genomic library for genes which, when introduced into Escherichia coli, suppressed secY24, a temperature sensitive mutation of an essential integral membrane protein (SecY) required for protein export. We isolated and characterized a gene (YSY6) which improved the translocation of the OmpA protein in mutant strain IQ85(secY24). It could also suppress another mutant [rplO215(Am)], in which the level of expression of the SecY protein is decreased at high-temperature. The YSY6 gene encodes a small amphiphilic peptide consisting of 65 amino acids, which can be expressed in E. coli cells.

Yeast gene which suppresses the defect in protein export of a secY mutant of E. coli. Publishing Authors By Initials

M Sakaguchi,C Ueguchi,K Ito,T Omura,

For similar fungi: yeasts research abstracts see: fungi: yeasts research

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Yeast gene which suppresses the defect in protein export of a secY mutant of E. coli. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Journal of biochemistry

VOLUME: 109

Page Numbers: 799-802

Journal Abbreviation: J. Biochem.

ISSN: 0021-924X

DAY: 19

MONTH: Jun

YEAR: 1991

Yeast gene which suppresses the defect in protein export of a secY mutant of E. coli. Information

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LANGUAGE: eng

NlmUniqueID: 376600

Yeast gene which suppresses the defect in protein export of a secY mutant of E. coli. Keywords Mesh Terms:

KEYWORDS: Yeasts

MESH TERMS: genetics

Chemical & Substance for Abstract: Yeast gene which suppresses the defect in protein export of a secY mutant of E. coli. Information

Substance Name: Fungal Proteins

Registry Number: 0

Grant and Affiliation Information for Yeast gene which suppresses the defect in protein export of a secY mutant of E. coli.

AFFILIATION: Department of Molecular Biology, Graduate School of Medical Science, Kyushu University, Fukuoka.

Country: JAPAN

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MEDLINETA: J Biochem

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ACCESSION NUMBER: S69830

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