[Y-chromosome microdeletions as a prognostic marker of male infertility]

[Y-chromosome microdeletions as a prognostic marker of male infertility] Research Abstract Details 

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[Y-chromosome microdeletions as a prognostic marker of male infertility] Abstract Text:

The results of molecular-genetic study of Y-chromosome microdeletions in men with spermatogenesis failure and in patients with cryptorchism are presented. The molecular-genetic studies of regions AZFa, AZFb, AZFc in STS loci - sY84, sY86, sY127, sY134, sY254, sY255 and SRY gene have been performed. Y-chromosome microdeletions were detected in 13,3% infertile men with spermogram failure. The frequency of genetic (cyto- and molecular) abnormalities among boys with isolated cryptorchism was 4%. The results show the necessity of additional study ofgenetic factors ofcryptorchism development.

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MEDLINE DATE: 2008 Mar-Apr

[Y-chromosome microdeletions as a prognostic marker of male infertility] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: T?Sitologii?a i genetika

VOLUME: 42

Page Numbers: 46-50

Journal Abbreviation: Tsitol. Genet.

ISSN: 0564-3783

DAY: 16

MONTH: 07

YEAR: 2008

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LANGUAGE: ukr

NlmUniqueID: 101671

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Country: Ukraine

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MEDLINETA: Tsitol Genet

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