Weight-bearing, aerobic exercise increases markers of bone formation during short-term weight loss in overweight and obese men and women.

Weight-bearing, aerobic exercise increases markers of bone formation during short-term weight loss in overweight and obese men and women. Research Abstract Details 

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Weight-bearing, aerobic exercise increases markers of bone formation during short-term weight loss in overweight and obese men and women. Abstract Text:

Pamela S Hinton,R Scott Rector,Tom R Thomas,

We investigated the impact of weight-bearing, aerobic exercise- and diet-induced weight loss on markers of bone turnover during a larger study of changes in metabolic fitness during short-term weight reduction using a repeated-measures, within-subject experimental design. Subjects (N = 19) underwent 6 weeks of energy restriction (reduced by approximately 3140 kJ/d) and aerobic exercise ( approximately 1675 kJ/d, walking or jogging at 60% maximum oxygen consumption) to induce a 5% reduction in body weight. Bone turnover markers and hormones were measured in serum collected at baseline and after 6 weeks of weight loss. Despite a 5% reduction in body weight at week 6, markers of bone formation, osteocalcin, and bone alkaline phosphatase, were significantly increased, and resorption markers, C-terminal cross-links of type I collagen and soluble receptor activator of nuclear factor kappaB ligand, were unchanged after 6 weeks of energy restriction and exercise. The concentration of leptin was significantly reduced after weight loss, but insulin-like growth factor I (IGF-I) and cortisol levels were unaffected. In conclusion, weight-bearing, aerobic exercise training may favorably affect the balance between bone resorption and formation during weight loss.

Weight-bearing, aerobic exercise increases markers of bone formation during short-term weight loss in overweight and obese men and women. Publishing Authors By Initials

PS Hinton,RS Rector,TR Thomas,

For similar biomechanics: weight-bearing research abstracts see: biomechanics: weight-bearing research

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Weight-bearing, aerobic exercise increases markers of bone formation during short-term weight loss in overweight and obese men and women. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Metabolism: clinical and experimental

VOLUME: 55

Page Numbers: 1616-8

Journal Abbreviation: Metab. Clin. Exp.

ISSN: 0026-0495

DAY: 3

MONTH: Dec

YEAR: 2006

Weight-bearing, aerobic exercise increases markers of bone formation during short-term weight loss in overweight and obese men and women. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 375267

Weight-bearing, aerobic exercise increases markers of bone formation during short-term weight loss in overweight and obese men and women. Keywords Mesh Terms:

KEYWORDS: Weight-Bearing

MESH TERMS: blood

Chemical & Substance for Abstract: Weight-bearing, aerobic exercise increases markers of bone formation during short-term weight loss in overweight and obese men and women. Information

Substance Name: Alkaline Phosphatase

Registry Number: EC 3.1.3.1

Grant and Affiliation Information for Weight-bearing, aerobic exercise increases markers of bone formation during short-term weight loss in overweight and obese men and women.

AFFILIATION: Department of Nutritional Sciences, University of Missouri-Columbia, Columbia, MO 65211, USA. hintonp@missouri.edu

Country: United States

AGENCY: United States NIAMS

GRANT: T32 AR48523

ACRONYM: AR

MEDLINETA: Metabolism

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