Wegener's granulomatosis with extension to the cavernous sinus.

Wegener's granulomatosis with extension to the cavernous sinus. Research Abstract Details 

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Wegener's granulomatosis with extension to the cavernous sinus. Abstract Text:

Halim Fadil,Eduardo Gonzalez-Toledo,Roger E Kelley,Jennifer Henley,Halim Fadil,Eduardo Gonzalez-Toledo,Roger E Kelley,Jennifer Henley,

BACKGROUND: Wegener's granulomatosis (WG) is an uncommon inflammatory disease which rarely is reported to invade the cavernous sinus. OBJECTIVE: To report a case of cavernous sinus syndrome in a patient with longstanding pansinusitis who was found to have Wegener's granulomatosis. PATIENT: A 59-year-old African American woman presented with a 10-day history of increasing nasal congestion with loss of taste and a 5-day history of increasing right frontal head pain with visual blurring of the right eye. On exam, she was noted to have diminished visual acuity, an afferent pupillary defect, and mild proptosis on the right, along with a palsy of the right sixth cranial nerve. She had a contrast-enhancing inflammatory process of the sinuses, the right pterygopalatine fossa, and the cavernous sinus by computed tomographic (CT) and magnetic resonance (MRI) scans. RESULTS: Biopsy revealed a necrotizing granulomatous process compatible with Wegener's granulomatosis. She was switched from empiric anti-bacterial, anti-tuberculous, and anti-fungal therapy to prednisone and methotrexate. CONCLUSIONS: Cavernous sinus involvement in Wegener's granulomatosis is rare, but such a disease process needs to be considered in the differential diagnosis of cavernous sinus syndrome as this will influence the choice of therapy.

Wegener's granulomatosis with extension to the cavernous sinus. Publishing Authors By Initials

H Fadil,E Gonzalez-Toledo,RE Kelley,J Henley,H Fadil,E Gonzalez-Toledo,RE Kelley,J Henley,

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Wegener's granulomatosis with extension to the cavernous sinus. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: The Journal of the Louisiana State Medical Society

VOLUME: 159

Page Numbers: 212-4; quiz 214, 230

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ISSN: 0024-6921

DAY: 8

MONTH: 11

YEAR: 2007

Wegener's granulomatosis with extension to the cavernous sinus. Information

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LANGUAGE: eng

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Grant and Affiliation Information for Wegener's granulomatosis with extension to the cavernous sinus.

AFFILIATION: Department of Neurology, LSU Health Sciences Center, Shreveport, Louisiana, USA.

Country: United States

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MEDLINETA: J La State Med Soc

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