Weekly changes in basal metabolic rate with eight weeks of overfeeding.

Weekly changes in basal metabolic rate with eight weeks of overfeeding. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Weekly changes in basal metabolic rate with eight weeks of overfeeding. Abstract Text:

Ann M Harris,Michael D Jensen,James A Levine,Ann M Harris,Michael D Jensen,James A Levine,

OBJECTIVE: The contribution of basal metabolic rate (BMR) to weight gain susceptibility has long been debated. We wanted to examine whether BMR changes in a linear fashion with overfeeding. Our hypothesis was that BMR does not increase linearly with 1000-kcal/d overfeeding in lean healthy subjects over 8 weeks. The null hypothesis states that BMR increases linearly with 1000-kcal/d overfeeding in lean healthy subjects. RESEARCH METHODS AND PROCEDURES: Initially, 16 lean healthy sedentary subjects completed 2 weeks of weight maintenance feeding at the General Clinical Research Center. The subjects were then overfed by 1000 kcal/d over 8 weeks. BMR was measured under standard conditions each week using indirect calorimetry. RESULTS: Baseline BMR was 1693 +/- 154.5 kcal/d. BMR increased from 1711 +/- 201.3 kcal/d at week 1 of overfeeding to 1781 +/- 171.65 kcal/d at the second week of overfeeding (p = 0.05). BMR fell during the third week of overfeeding to 1729 +/- 179.5 kcal/d (p = 0.05). After 5 weeks of overfeeding, BMR reached a plateau. Thereafter, there was no further change. Comparison of BMR with weeks of overfeeding was significantly different compared with the linear model (p < 0.05). DISCUSSION: Increases in BMR in lean sedentary healthy subjects with 1000-kcal/d overfeeding are not linear over 8 weeks. There seems to be a short-term increase in BMR in the first 2 weeks of overfeeding that is not representative of longer-term changes.

Weekly changes in basal metabolic rate with eight weeks of overfeeding. Publishing Authors By Initials

AM Harris,MD Jensen,JA Levine,AM Harris,MD Jensen,JA Levine,

For similar nutritional and metabolic diseases: nutrition disorders: overnutrition research abstracts see: nutritional and metabolic diseases: nutrition disorders: overnutrition research

PUBMED ID PMID:

MEDLINE DATE:

Weekly changes in basal metabolic rate with eight weeks of overfeeding. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Obesity (Silver Spring, Md.)

VOLUME: 14

Page Numbers: 690-5

Journal Abbreviation:

ISSN: 1930-7381

DAY: 3

MONTH: Apr

YEAR: 2006

Weekly changes in basal metabolic rate with eight weeks of overfeeding. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 101264860

Weekly changes in basal metabolic rate with eight weeks of overfeeding. Keywords Mesh Terms:

KEYWORDS: Overnutrition

MESH TERMS: metabolism

Chemical & Substance for Abstract: Weekly changes in basal metabolic rate with eight weeks of overfeeding. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Weekly changes in basal metabolic rate with eight weeks of overfeeding.

AFFILIATION: Endocrine Research Unit, Mayo Clinic, Rochester, MN 55905, USA.

Country: United States

AGENCY: United States NCRR

GRANT: M01 RR00585

ACRONYM: RR

MEDLINETA: Obesity (Silver Spring)

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Weekly changes in basal metabolic rate with eight weeks of overfeeding Related Publications

• Aberrant crypt foci in patients with a positive family history of sporadic colorectal cancer.
• Autophagy gene-dependent clearance of apoptotic cells during embryonic development.
• Cancer and myositis: new insights into an old association.
• Cascade model of ventricular-arterial coupling and arterial-cardiac baroreflex function for cardiovascular variability in humans.
• Chondroblastoma of the temporal bone: consistent middle fossa involvement.
• Daptomycin for infective endocarditis.
• Defects in retinal pigment epithelium cell proliferation and retinal attachment in mutant mice with p27(Kip1) gene ablation.
• Dopamine reduction of GABA currents in striatal medium-sized spiny neurons is mediated principally by the D(1) receptor subtype.
• Dysfunctional channels are making noise in CAG triplet repeat disorders.
• Effects of alcohol on group formation among male social drinkers.
• Energy expenditure of sedentary screen time compared with active screen time for children.
• Evolution of the ventral midline in insect embryos.
• GATA factors participate in tissue-specific immune responses in Drosophila larvae.
• Galectin-3 stimulates preadipocyte proliferation and is up-regulated in growing adipose tissue.
• HES6 reverses nuclear reprogramming of insulin-producing cells following cell fusion.
• Left ventricular aneurysmectomy: tailored scar excision and linear closure.
• MDM2 SNP309 accelerates colorectal tumour formation in women.
• MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia.
• Mechanically-evoked C-fiber activity in painful alcohol and AIDS therapy neuropathy in the rat.
• Orexin A mediation of time spent moving in rats: neural mechanisms.
• Pathologic complete response may not represent the optimal surrogate for survival after preoperative therapy for esophageal cancer.
• Professionalism and evolving concepts of quality.
• Reconstruction of complicated skull base defects utilizing free tissue transfer.
• Sources of beta-Cells for Human Cell-Based Therapies for Diabetes.
• Steroid hormone activation of wandering in the isolated nervous system of Manduca sexta.
• Surfactant protein D regulates the cell surface expression of alveolar macrophage beta(2)-integrins.
• The global market for ADHD medications.
• Transfusion related acute lung injury in cardiac surgery.
• TrkA and PKC-epsilon in thermal burn-induced mechanical hyperalgesia in the rat.
• Weekly changes in basal metabolic rate with eight weeks of overfeeding.