Waist circumference and waist-to-hip ratio as predictors of cardiovascular events: meta-regression analysis of prospective studies.

Waist circumference and waist-to-hip ratio as predictors of cardiovascular events: meta-regression analysis of prospective studies. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Waist circumference and waist-to-hip ratio as predictors of cardiovascular events: meta-regression analysis of prospective studies. Abstract Text:

Lawrence de Koning,Anwar T Merchant,Janice Pogue,Sonia S Anand,Lawrence de Koning,Anwar T Merchant,Janice Pogue,Sonia S Anand,Lawrence de Koning,Anwar T Merchant,Janice Pogue,Sonia S Anand,

AIMS: The objectives of this study were to determine the association of waist circumference (WC) and waist-to-hip ratio (WHR) with the risk of incident cardiovascular disease (CVD) events and to determine whether the strength of association of WC and WHR with CVD risk is different. METHODS AND RESULTS: This meta-regression analysis used a search strategy of keywords and MeSH terms to identify prospective cohort studies and randomized clinical trials of CVD risk and abdominal obesity from the Medline, Embase, and Cochrane databases. Fifteen articles (n = 258 114 participants, 4355 CVD events) reporting CVD risk by categorical and continuous measures of WC and WHR were included. For a 1 cm increase in WC, the relative risk (RR) of a CVD event increased by 2% (95% CI: 1-3%) overall after adjusting for age, cohort year, or treatment. For a 0.01 U increase in WHR, the RR increased by 5% (95% CI: 4-7%). These results were consistent in men and women. Overall risk estimates comparing the extreme quantiles of each measure suggested that WHR was more strongly associated with CVD than that for WC (WHR: RR = 1.95, 95% CI: 1.55-2.44; WC: RR = 1.63, 95% CI: 1.31-2.04), although this difference was not significant. The strength of association for each measure was similar in men and women. CONCLUSION: WHR and WC are significantly associated with the risk of incident CVD events. These simple measures of abdominal obesity should be incorporated into CVD risk assessments.

Waist circumference and waist-to-hip ratio as predictors of cardiovascular events: meta-regression analysis of prospective studies. Publishing Authors By Initials

L de Koning,AT Merchant,J Pogue,SS Anand,L de Koning,AT Merchant,J Pogue,SS Anand,L de Koning,AT Merchant,J Pogue,SS Anand,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Waist circumference and waist-to-hip ratio as predictors of cardiovascular events: meta-regression analysis of prospective studies. Journal Published:

PUBLICATION TYPE: Review

Journal: European heart journal

VOLUME: 28

Page Numbers: 850-6

Journal Abbreviation:

ISSN: 0195-668X

DAY: 2

MONTH: 04

YEAR: 2007

Waist circumference and waist-to-hip ratio as predictors of cardiovascular events: meta-regression analysis of prospective studies. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 8006263

Waist circumference and waist-to-hip ratio as predictors of cardiovascular events: meta-regression analysis of prospective studies. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Waist circumference and waist-to-hip ratio as predictors of cardiovascular events: meta-regression analysis of prospective studies. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Waist circumference and waist-to-hip ratio as predictors of cardiovascular events: meta-regression analysis of prospective studies.

AFFILIATION: Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada L8L 2X2.

Country: England

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Eur Heart J

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Waist circumference and waist-to-hip ratio as predictors of cardiovascular events: meta-regression analysis of prospective studies Related Publications

• Adverse swelling associated with use of rh-BMP-2 in anterior cervical discectomy and fusion: a case study.
• Anaesthetic neurotoxicity in rodents: is the ketamine controversy real?
• Applying the gender lens to abdominal aortic aneurysm screening.
• Comparison of epilenticular IOL implantation vs technique of anterior and primary posterior capsulorhexis with anterior vitrectomy in paediatric cataract surgery.
• Computer aided analysis of phonocardiogram.
• Current controversies regarding pain assessment in neonates.
• Effect of egg yolk lipids on the freezing of goat semen.
• Fears and beliefs of patients regarding cardiac catheterization.
• Giant villous adenoma presenting as a mass protruding from the rectum in a 29-year-old female patient.
• Impact of external haematology proficiency testing programme on quality of laboratories.
• Is too much neurohormonal blockade harmful?
• Isolated intraorbital metastasis in breast carcinoma.
• Labelled cleanable sheeting to facilitate microvascular clamp identification.
• Late graft loss or death in pediatric liver transplantation: an analysis of the SPLIT database.
• Malaria parasite burden and treatment seeking behavior in ethnic communities of Assam, Northeastern India.
• Mechanisms of synergy between alcohol and hepatitis C virus.
• Microwave enhanced polarization in a carbon dioxide molecule.
• Neurobehavior of preterm infants at 36 weeks postconception as a function of morphine analgesia.
• Neurodevelopmental changes of fetal pain.
• Neuronal markers in allergic rhinitis: expression and correlation with sensory testing.
• Non-pharmacological techniques for pain management in neonates.
• Pain assessment in preterm neonates.
• Pharmacological approaches to the management of pain in the neonatal intensive care unit.
• Premedication for tracheal intubation in neonates: confusion or controversy?
• Seeing through the blind! Ability of hospital staff to differentiate morphine from placebo, in neonates at a placebo controlled trial.
• Sex and gender subgroup analyses of randomized trials the need to proceed with caution.
• Studies on sorption of Cd(II) on Tata chromite mine overburden.
• Voltage-gated ion channel Na(v)1.7 innervation in patients with idiopathic rectal hypersensitivity and paroxysmal extreme pain disorder (familial rectal pain).
• Waist circumference and waist-to-hip ratio as predictors of cardiovascular events: meta-regression analysis of prospective studies.
• Yoga in premature ejaculation: a comparative trial with fluoxetine.