Vitamin K deficiency bleeding with intracranial hemorrhage: focus on secondary form.

Vitamin K deficiency bleeding with intracranial hemorrhage: focus on secondary form. Research Abstract Details 

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Vitamin K deficiency bleeding with intracranial hemorrhage: focus on secondary form. Abstract Text:

Mikiko Miyasaka,Shunsuke Nosaka,Hirokazu Sakai,Yoshiyuki Tsutsumi,Masayuki Kitamura,Osamu Miyazaki,Ikuko Okusu,Kyoko Kashima,Reiko Okamoto,Chihiro Tani,Yoshiyuki Okada,Hidekazu Masaki,Mikiko Miyasaka,Shunsuke Nosaka,Hirokazu Sakai,Yoshiyuki Tsutsumi,Masayuki Kitamura,Osamu Miyazaki,Ikuko Okusu,Kyoko Kashima,Reiko Okamoto,Chihiro Tani,Yoshiyuki Okada,Hidekazu Masaki,

Non-accidental trauma is the leading cause of intracranial hemorrhage (ICH) in infancy. In contrast, ICH as a part of vitamin K deficiency bleeding (VKDB) secondary to hepatobiliary disease is rare, but encountered even in the era of vitamin K (VK) prophylaxis. During 43 months, six cases with ICH were diagnosed as an initial presentation of VKDB. Clinical features and imaging findings of them were retrospectively reviewed. All cases were breastfed and received oral VK prophylaxis. Liver dysfunction was found in five. Brain CT showed hemorrhage in subdural and subarachnoid space in six, parenchyma in three, and ventricle in one. Abdominal ultrasound was positive in four with final diagnoses of biliary atresia in two, neonatal hepatitis in one, and milk allergy in one. Two cases with negative ultrasound were diagnosed as idiopathic VKDB. In conclusion, ICH with secondary VKDB is rare, but important in infancy in the era of VK prophylaxis.

Vitamin K deficiency bleeding with intracranial hemorrhage: focus on secondary form. Publishing Authors By Initials

M Miyasaka,S Nosaka,H Sakai,Y Tsutsumi,M Kitamura,O Miyazaki,I Okusu,K Kashima,R Okamoto,C Tani,Y Okada,H Masaki,M Miyasaka,S Nosaka,H Sakai,Y Tsutsumi,M Kitamura,O Miyazaki,I Okusu,K Kashima,R Okamoto,C Tani,Y Okada,H Masaki,

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Vitamin K deficiency bleeding with intracranial hemorrhage: focus on secondary form. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Emergency radiology

VOLUME: 14

Page Numbers: 323-9

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ISSN: 1070-3004

DAY: 5

MONTH: 09

YEAR: 2007

Vitamin K deficiency bleeding with intracranial hemorrhage: focus on secondary form. Information

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LANGUAGE: eng

NlmUniqueID: 9431227

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AFFILIATION: Department of Radiology, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo 157-8535, Japan. miyasaka-m@ncchd.go.jp

Country: United States

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MEDLINETA: Emerg Radiol

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