Visuospatial working memory in school-aged children exposed in utero to cocaine.

Visuospatial working memory in school-aged children exposed in utero to cocaine. Research Abstract Details 

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Visuospatial working memory in school-aged children exposed in utero to cocaine. Abstract Text:

Linda Mayes,Peter J Snyder,Eric Langlois,Nicole Hunter,

OBJECTIVE: Among the neurocognitive impairments reported as associated with prenatal cocaine exposure, slower response time, and less efficient learning in school-aged children are common to findings from several laboratories. This study presents performance data on a spatial working memory task in 75 prenatally cocaine exposed (CE) and 55 nondrug-exposed (NDE) 8- to 10-year-old children. METHODS: Children were administered a novel neuropsychological measure of immediate- and short-term memory for visuospatial information, the Groton Maze Learning Test (GMLT), a computer-based hidden maze learning test that consists of a "timed chase test" (a simple measure of visuomotor speed), eight learning trials followed by a delayed recall trial after an 8-minute delay and a reverse learning trial. Performance is expressed as correct moves per second and number of errors per trial. RESULTS: Across all trials, the cocaine-exposed group showed significantly slower correct moves per second and made significantly more errors. There were no significant main effects for amounts of alcohol, tobacco, or marijuana exposure. After an 8-minute delay and compared to the eighth trial, cocaine-exposed children showed less consolidation in learning compared to nonexposed children. When asked to complete the maze in reverse, cocaine-exposed children showed a greater decrement in performance (decreased correct moves per second and increased errors) compared to the eighth learning trial. CONCLUSIONS: Children exposed in utero to cocaine exhibit a possible impairment in procedural learning and diminished efficiency in creating and accessing an internal spatial map to master the hidden maze.

Visuospatial working memory in school-aged children exposed in utero to cocaine. Publishing Authors By Initials

L Mayes,PJ Snyder,E Langlois,N Hunter,

For similar psychological phenomena and processes: mental processes: perception: visual perception research abstracts see: psychological phenomena and processes: mental processes: perception: visual perception research

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Visuospatial working memory in school-aged children exposed in utero to cocaine. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Child neuropsychology : a journal on normal and ab

VOLUME: 13

Page Numbers: 205-18

Journal Abbreviation:

ISSN: 0929-7049

DAY: 3

MONTH: May

YEAR: 2007

Visuospatial working memory in school-aged children exposed in utero to cocaine. Information

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LANGUAGE: eng

NlmUniqueID: 9512515

Visuospatial working memory in school-aged children exposed in utero to cocaine. Keywords Mesh Terms:

KEYWORDS: Visual Perception

MESH TERMS: epidemiology

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Grant and Affiliation Information for Visuospatial working memory in school-aged children exposed in utero to cocaine.

AFFILIATION: Yale Child Study Center, Yale University School of Medicine, New Haven, CT 06520, USA.

Country: Netherlands

AGENCY: United States NIDA

GRANT: R01-DA-06025

ACRONYM: DA

MEDLINETA: Child Neuropsychol

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