Retroviridae

- A novel lysophospholipid- and pH-sensitive receptor, GPR4, in brain endothelial cells regulates monocyte transmigration. Abundant evidence documents the highly proinflammatory actions of lysophosphatidylcholine (LPC). Further, LPC, found in high amounts in oxidized low-density...

- AKT induces senescence in primary esophageal epithelial cells but is permissive for differentiation as revealed in organotypic culture. Epidermal growth factor receptor (EGFR) overexpression and activation is critical in the initiation and progression of cancers, especially those of...

- Application of an enzyme-linked immunosorbent assay (ELISA) involving monoclonal antibody for detection of BLV antibodies in individual or pooled bovine milk samples.

- Basic principles of gene transfer in hematopoietic stem cells.

- Bovine leukosis in Nigeria--a preliminary study.

- Coordinate suppression of ERBB2 and ERBB3 by enforced expression of micro-RNA miR-125a or miR-125b. Deregulation of micro-RNAs (miRNAs) is emerging as a major aspect of cancer etiology because their capacity to direct the translation and stability of...

- Correction of clinical manifestations of canine mucopolysaccharidosis I with neonatal retroviral vector gene therapy. Mucopolysaccharidosis I (MPS I) (Hurler syndrome) is due to deficient alpha-L-iduronidase (IDUA) activity and is the most common of the MPS disorders....

- Cutting edge: treatment of complement regulatory protein deficiency by retroviral in vivo gene therapy. Gene therapy is an attractive means to replace a deficient or defective protein. Using a murine retroviral vector, we provide an example of reconstituting a...

- Darwin's surprise: why are evolutionary biologists bringing back extinct deadly viruses?

- Detection of precipitating antibodies and identification of bovine leukemia virus antigens by micro counter-current immunoelectrophoresis.

- Determination of lymphocyte count necessary for isolating bovine leukaemia virus (BLV) from BLV-infected cattle and correlation between lymphocyte count and antibody titre.

- Didanosine, a new antiretroviral drug. A review. In this article the literature about didanosine, an antiretroviral drug, is reviewed. The mechanism of action, biochemical pharmacology, pharmacokinetics,...

- Efficient generation of random chromosome deletions.

- Endogenous retroviral sequences in the pathogenesis of systemic autoimmune disease. OBJECTIVES: To update information on endogenous retroviral sequences and discuss their role in systemic autoimmune disease. DATA SOURCES: Articles retrieved...

- Enhancement of retroviral gene transduction on a dish coated with a cocktail of two different polypeptides: one exhibiting binding activity toward target cells, and the other toward retroviral vectors. CH-296, a recombinant fragment of human fibronectin (FN) composed of the cell-binding domain (C-domain), heparin-binding domain II (H-domain), and CS1 site,...

- Evidence for the presence of RNA tumor virus components in human leukemia.

- Exploring carcinogenesis with retroviral and cellular oncogenes.

- Frequency of lymphocytes bearing surface membrane immunoglobulins in leukaemic cattle.

- Genetic and epigenetic susceptibility to endogenous retrovirus-induced lymphomas in SL mice.

- Genomic instability during Myc-induced lymphomagenesis in the bursa of Fabricius. Retroviral vector-mediated overexpression of c-myc in embryonic bursal precursors induces multi-staged tumorigenesis beginning with preneoplastic-transformed...