Versatile bioelectronic interfaces on flexible non-conductive substrates.

Versatile bioelectronic interfaces on flexible non-conductive substrates. Research Abstract Details 

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Versatile bioelectronic interfaces on flexible non-conductive substrates. Abstract Text:

Bioelectronic interfaces that establish electrical communication between redox enzymes and electrodes have potential applications as biosensors, biocatalytic reactors, and biological fuel cells. These interfaces are commonly formed on gold films deposited using physical vapor deposition (PVD) or chemical vapor deposition (CVD). PVD and CVD require deposition of a primer layer, such as titanium or chromium, and require the use of expensive equipment and cannot be used on a wide range of substrates. This paper describes a versatile new bench-top method to form bioelectronic interfaces containing a gold film, electron mediator, cofactor, and dehydrogenase enzyme (secondary alcohol dehydrogenase, and sorbitol dehydrogenase) on nonconductive substrates such as polystyrene and glass. The method combines layer-by-layer deposition of polyelectrolytes, electroless metal deposition, and directed molecular self-assembly. Cyclic voltammetry, chronoamperometry, field emission X-ray dispersive spectroscopy, scanning electron microscopy, and atomic force microscopy were used to characterize the bioelectronic interfaces. Interfaces formed on flexible polystyrene slides were shown to retain their activity after bending to a radius of curvature of 18mm, confirming that the approach can be applied on cheap and flexible substrates for applications where traditional wafer-scale electronics is not suitable, such as personal or structural health monitors and rolled microtube biosensors.

Versatile bioelectronic interfaces on flexible non-conductive substrates. Publishing Authors By Initials

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Versatile bioelectronic interfaces on flexible non-conductive substrates. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Biosensors & bioelectronics

VOLUME: 23

Page Numbers: 1481-7

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ISSN: 0956-5663

DAY: 15

MONTH: 01

YEAR: 2008

Versatile bioelectronic interfaces on flexible non-conductive substrates. Information

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LANGUAGE: eng

NlmUniqueID: 9001289

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Grant and Affiliation Information for Versatile bioelectronic interfaces on flexible non-conductive substrates.

AFFILIATION: Department of Chemical Engineering and Materials Science, Michigan State University, East Lansing, MI 48824, United States.

Country: England

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MEDLINETA: Biosens Bioelectron

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