Venous thromboembolism in a general hospital. An update with low molecular weight heparin prophylaxis.

Venous thromboembolism in a general hospital. An update with low molecular weight heparin prophylaxis. Research Abstract Details 

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Venous thromboembolism in a general hospital. An update with low molecular weight heparin prophylaxis. Abstract Text:

S L Schulz,C Kesselring,U Seeberger,D Andresen,

BACKGROUND: Patients admitted to hospital for surgery or acute medical illnesses have a high risk for venous thromboembolism (VTE). Today's widespread use of low molecular weight heparins (LMWH) for VTE prophylaxis is supposed to have reduced VTE rates substantially. However, data concerning the overall effectiveness of LMWH prophylaxis is sparse. PATIENTS AND METHODS: We prospectively studied all patients with symptomatic and objectively confirmed VTE seen in our hospital over a three year period. Event rates in different wards were analysed and compared. VTE prophylaxis with Enoxaparin was given to all patients at risk during their hospital stay. RESULTS: A total of 50 464 inpatients were treated during the study period. 461 examinations were carried out for symptoms suggestive of VTE and yielded 89 positive results in 85 patients. Seventy eight patients were found to have deep vein thrombosis, 7 had pulmonary embolism, and 4 had both deep venous thrombosis and pulmonary embolism. The overall in hospital VTE event rate was 0.17%. The rate decreased during the study period from 0.22 in year one to 0,16 in year two and 0.13 % in year three. It ranged highest in neurologic and trauma patients (0.32%) and lowest (0.08%) in gynecology-obstetrics. CONCLUSIONS: With a simple and strictly applied regimen of prophylaxis with LMWH the overall rate of symptomatic VTE was very low in our hospitalized patients. Beside LMWH prophylaxis, shortening hospital stays and substantial improvements in surgical and anesthesia techniques achieved during the last decades probably play an essential role in decreasing VTE rates.

Venous thromboembolism in a general hospital. An update with low molecular weight heparin prophylaxis. Publishing Authors By Initials

SL Schulz,C Kesselring,U Seeberger,D Andresen,

For similar cardiovascular diseases: vascular diseases: embolism and thrombosis: thrombosis: venous thrombosis research abstracts see: cardiovascular diseases: vascular diseases: embolism and thrombosis: thrombosis: venous thrombosis research

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Venous thromboembolism in a general hospital. An update with low molecular weight heparin prophylaxis. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: VASA. Zeitschrift für Gefässkrankheiten. Journal f

VOLUME: 36

Page Numbers: 17-22

Journal Abbreviation: VASA

ISSN: 0301-1526

DAY: 13

MONTH: Feb

YEAR: 2007

Venous thromboembolism in a general hospital. An update with low molecular weight heparin prophylaxis. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 317051

Venous thromboembolism in a general hospital. An update with low molecular weight heparin prophylaxis. Keywords Mesh Terms:

KEYWORDS: Venous Thrombosis

MESH TERMS: ultrasonography

Chemical & Substance for Abstract: Venous thromboembolism in a general hospital. An update with low molecular weight heparin prophylaxis. Information

Substance Name: Enoxaparin

Registry Number: 0

Grant and Affiliation Information for Venous thromboembolism in a general hospital. An update with low molecular weight heparin prophylaxis.

AFFILIATION: Vivantes Klinikum Am Urban Berlin, Germany. susanne.schulz@vivantes.de

Country: Switzerland

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MEDLINETA: Vasa

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