Vasopressor Use in the Critical Care Unit for Treatment of Persistent Post-carotid Artery Stent Induced Hypotension.

Vasopressor Use in the Critical Care Unit for Treatment of Persistent Post-carotid Artery Stent Induced Hypotension. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Vasopressor Use in the Critical Care Unit for Treatment of Persistent Post-carotid Artery Stent Induced Hypotension. Abstract Text:

Mohan Reddi Nandalur,Howard Cooper,Lowell F Satler,Kiran R Nandalur,John R Laird,Mohan Reddi Nandalur,Howard Cooper,Lowell F Satler,Kiran R Nandalur,John R Laird,Mohan Reddi Nandalur,Howard Cooper,Lowell F Satler,Kiran R Nandalur,John R Laird,

INTRODUCTION: Hypotension is common following carotid artery stenting (CAS), and may be mediated by vagal stimulation and/or suppression of spinal sympathetic outflow. Both mixed alpha/beta agonists (dopamine (DA)), and more selective alpha- agonists (norepinephrine (NE) and phenylephrine (PE)), have been used, but the most effective treatment of post-CAS hypotension is unknown. MATERIALS AND METHODS: We analyzed data for consecutive patients requiring vasopressor treatment of post-CAS hypotension. The treating physician made choice of vasopressor. Endpoints included infusion duration, coronary care unit (CCU) length of stay (LOS), and any major adverse events (death, stroke, myocardial infarction, arrhythmia). RESULTS: During the study period, CAS stenting was performed in 623 patients. CCU admission in atropine non-responders for vasopressor treatment was required in 42 patients (6.7%). DA was used in 20 patients (48%), NE in 13 patients (31%), and PE in nine patients (21%). Vasopressor infusion time was 31.8 +/- 10.6 h for DA, compared with 23.8 +/- 8.1 h for NE (P = 0.052) and 22.1 +/- 6.1 h (P = 0.028) for PE. CCU LOS was 46.5 +/- 14.1 h for DA compared with 36.9 +/- 9.1 h for the NE and PE groups combined (P = 0.056). Major adverse events were more common in patients receiving DA than among patients receiving NE or PE (P = 0.04). CONCLUSIONS: Compared with DA, treatment of post-CAS hypotension with a selective alpha-agonist (NE or PE) is associated with shorter drug infusion time, shorter CCU LOS, and fewer major adverse events.

Vasopressor Use in the Critical Care Unit for Treatment of Persistent Post-carotid Artery Stent Induced Hypotension. Publishing Authors By Initials

MR Nandalur,H Cooper,LF Satler,KR Nandalur,JR Laird,MR Nandalur,H Cooper,LF Satler,KR Nandalur,JR Laird,MR Nandalur,H Cooper,LF Satler,KR Nandalur,JR Laird,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Vasopressor Use in the Critical Care Unit for Treatment of Persistent Post-carotid Artery Stent Induced Hypotension. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Neurocritical care

VOLUME: 7

Page Numbers: 232-7

Journal Abbreviation:

ISSN: 1541-6933

DAY: 16

MONTH: 11

YEAR: 2007

Vasopressor Use in the Critical Care Unit for Treatment of Persistent Post-carotid Artery Stent Induced Hypotension. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 101156086

Vasopressor Use in the Critical Care Unit for Treatment of Persistent Post-carotid Artery Stent Induced Hypotension. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Vasopressor Use in the Critical Care Unit for Treatment of Persistent Post-carotid Artery Stent Induced Hypotension. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Vasopressor Use in the Critical Care Unit for Treatment of Persistent Post-carotid Artery Stent Induced Hypotension.

AFFILIATION: Division of Cardiovascular Medicine, Washington Hospital Center and Georgetown University, 106 Irving st NW, #3200N, Washington, DC, 20010, USA, Nandalur@hotmail.com.

Country: United States

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Neurocrit Care

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Vasopressor Use in the Critical Care Unit for Treatment of Persistent Post-carotid Artery Stent Induced Hypotension Related Publications

• 976.
• A histological study of the latent period of hepatoma grafts.
• A new multimarker test for family-based association studies.
• An efficient family-based association test using multiple markers.
• Caveolin-1 and -2 interact with connexin43 and regulate gap junctional intercellular communication in keratinocytes.
• Closing the gap on autosomal dominant connexin-26 and connexin-43 mutants linked to human disease.
• Connexin levels regulate keratinocyte differentiation in the epidermis.
• Connexins and gap junctions in mammary gland development and breast cancer progression.
• DIRECT UNIT PHENOL COEFFICIENT: A NEW METHOD.
• DNA methylation profiles of gastric carcinoma characterized by quantitative DNA methylation analysis.
• Decreased levels of connexin43 result in impaired development of the mammary gland in a mouse model of oculodentodigital dysplasia.
• Differentiation of organotypic epidermis in the presence of skin disease-linked dominant-negative cx26 mutants and knockdown cx26.
• EFBAT: exact family-based association tests.
• Encoding PCR Products with Batch-stamps and Barcodes.
• Epigenetic stem cell signature in cancer.
• Excimer laser assisted angioplasty for complex infrainguinal peripheral artery disease: a 2008 update.
• Fabellar joint causing pain after total knee replacement.
• HAND DISINFECTION-AN INVESTIGATION OF VARIOUS PREPARATIONS FOR THIS PURPOSE.
• Incorporating missingness for estimation of marginal regression models with multiple source predictors.
• Inpatient care in a community hospital: comparing length of stay and costs among teaching, hospitalist, and community services.
• LongCriSP: a test for bump hunting in longitudinal data.
• Overview of new technologies for lower extremity revascularization.
• Pannexin 1 and pannexin 3 are glycoproteins that exhibit many distinct characteristics from the connexin family of gap junction proteins.
• Screening for middle ear disease in a school for the deaf.
• Smad3 deficiency promotes tumorigenesis in the distal colon of ApcMin/+ mice.
• The Determination of the Value of Certain Soaps in Disinfecting Wall and Floor Surfaces.
• Use of stent grafts and coils in vessel rupture and perforation.
• Vasopressor Use in the Critical Care Unit for Treatment of Persistent Post-carotid Artery Stent Induced Hypotension.
• Why does zeno the stoic hold his breath? "Zenoism" as a new variable for studying suicide.
• [Editorial: Insects from elsewhere]