Vascular osteomuscular autograft prefabrication using coral, type I collagen and recombinant human bone morphogenetic protein-2.

Vascular osteomuscular autograft prefabrication using coral, type I collagen and recombinant human bone morphogenetic protein-2. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Vascular osteomuscular autograft prefabrication using coral, type I collagen and recombinant human bone morphogenetic protein-2. Abstract Text:

Q Ma,T Mao,B Liu,J Zhao,F Chen,H Wang,M Zhao,

In 20 male Sprague-Dawley rats, 10 pieces of L-shaped coral combined with type I collagen and recombinant human bone morphogenetic protein-2 (rhBMP-2) and 10 discs (diameter 5 mm) were wrapped in the gracilis muscle, and left pedicled on the femoral vessels. Untreated coral was buried in muscle at a distant control site in 4 animals. After 3 weeks, autografts were examined for the shape of new bone, vascular patency, and induction of bone. In all grafts in viable tissue, heterotopic bone was formed. The shape of the new bone was the same as that of the coral, and there was no significant inflammatory reaction. Part of the coral in the composite was absorbed. Bone was not formed in any of the control sites. Coral and type 1 collagen are effective as a carrier for BMP to prefabricate vascular osteomuscular autografts with designed shape. There is a potential clinical application for BMP to bioengineer microvascular free flaps with intrinsic skeletal muscle for maxillofacial reconstruction.

Vascular osteomuscular autograft prefabrication using coral, type I collagen and recombinant human bone morphogenetic protein-2. Publishing Authors By Initials

Q Ma,T Mao,B Liu,J Zhao,F Chen,H Wang,M Zhao,

For similar surgical procedures, operative: transplantation: transplantation, autologous research abstracts see: surgical procedures, operative: transplantation: transplantation, autologous research

PUBMED ID PMID:

MEDLINE DATE:

Vascular osteomuscular autograft prefabrication using coral, type I collagen and recombinant human bone morphogenetic protein-2. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: The British journal of oral & maxillofacial surger

VOLUME: 38

Page Numbers: 561-4

Journal Abbreviation:

ISSN: 0266-4356

DAY: 19

MONTH: Oct

YEAR: 2000

Vascular osteomuscular autograft prefabrication using coral, type I collagen and recombinant human bone morphogenetic protein-2. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 8405235

Vascular osteomuscular autograft prefabrication using coral, type I collagen and recombinant human bone morphogenetic protein-2. Keywords Mesh Terms:

KEYWORDS: Transplantation, Autologous

MESH TERMS: pathology

Chemical & Substance for Abstract: Vascular osteomuscular autograft prefabrication using coral, type I collagen and recombinant human bone morphogenetic protein-2. Information

Substance Name: Collagen

Registry Number: 9007-34-5

Grant and Affiliation Information for Vascular osteomuscular autograft prefabrication using coral, type I collagen and recombinant human bone morphogenetic protein-2.

AFFILIATION: Department of Oral and Maxillofacial Surgery, Dental School, Fourth Military Medical University, Xi'an, People's Republic of China.

Country: SCOTLAND

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Br J Oral Maxillofac Surg

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Vascular osteomuscular autograft prefabrication using coral, type I collagen and recombinant human bone morphogenetic protein-2 Related Publications

• Cooperation of endoderm-derived BMP2 and extraembryonic ectoderm-derived BMP4 in primordial germ cell generation in the mouse.
• Effect of vitamin E succinate on expression of TGF-beta1, c-Jun and JNK1 in human gastric cancer SGC-7901 cells.
• Roles of Fas signaling pathway in vitamin E succinate-induced apoptosis in human gastric cancer SGC-7901 cells.
• Vascular osteomuscular autograft prefabrication using coral, type I collagen and recombinant human bone morphogenetic protein-2.
• [Acute physiology and chronic health evaluation II system to prevent and treat infection in surgical ICU]
• [An experimental study on the effect of xenogeneic bone combined with human recombinant bone morphogenetic protein-2]
• [Anterior instrumentation for the treatment of tuberculotic spinal deformity]
• [Arthrowand technique under arthroscope in diagnosis and treatment of knee disease]
• [Breast ptosis correction with a knitted polypropylene mesh]
• [Changes in autoantibody against cardiovascular AT1-receptor during development of renovascular hypertension in rats]
• [Characters of uncoupling protein and its relation with obesity]
• [Classification and treatment of asymmetrical breast deformity]
• [Clinical analysis of 44 cases of recurrent thyroid carcinoma]
• [Clinico-pathologic and prognostic studies on lung adenocarcinoma patients under 40 years of age]
• [Comparative study of human fetal and adult bone marrow derived mesenchymal stem cells]
• [Different serum lipid adjustment drugs for the treatment of hyperlipidemic fatty liver]
• [Effects of air pollution from burning coal on respiratory diseases in adults]
• [Expression of protooncogene c-jun, p38 and proliferating cell nuclear antigen in intestinal epithelial cells in rats different development stages]
• [Inhibition of human gastric carcinoma cell growth by vitamin E succinate]
• [Isolation and identification of chemical constituents from Albizia julibrissin Durazz.]
• [Peritoneal lavage cytology in 66 patients with gastric carcinoma]
• [Relationship between endotracheal intubation pattern and nosocomial infection of medical staff during treatment of severe acute respiratory syndrome]
• [Research on embryonic stem cells]
• [State of the art in the study of postburn ischemic/hypoxic injury]
• [Study of autofluorescence spectrum of dilute gastric juice in the diagnosis of gastric carcinoma]
• [Study on the chemical components of edible oil fume in kitchen and its genotoxity on Drosophila]
• [Study on vitamin E succinate inducing apoptosis of human gastric carcinoma cell]
• [Survey of taenia saginata infection in students in Harbin city]
• [The clinical staging and tissue bacterial quantification in the diagnosis of burn wound sepsis]
• [Ultrasonically guided radio-frequency ablation of liver tumors with a clustered electrode: a report of 100 cases]