[Vascular endothelial growth factor expression in focal cerebral ischemia/reperfusion in injury in rats]

[Vascular endothelial growth factor expression in focal cerebral ischemia/reperfusion in injury in rats] Research Abstract Details 

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[Vascular endothelial growth factor expression in focal cerebral ischemia/reperfusion in injury in rats] Abstract Text:

Ying Xing,Zhong-xin Xu,Jing Mang,Jia-li Qian,

OBJECTIVE: To study the vascular endothelial growth factor (VEGF) expression and its role in focal cerebral ischemia/reperfusion injury.METHODS: VEGF protein and mRNA expressions at the site of focal ischemia/reperfusion of rat cerebrum were assessed with immunohistochemistry and hybridization techniques. RESULTS: In normal cerebral tissue there was lower expression of VEGF. It was found to be expressed in the penumbra area after ischemia. With the prolongation of ischemia and ischemia/reperfusion, enhanced expression of VEGF tended to decline to normal level, while it enhanced in the penumbra area.CONCLUSION: Enhanced VEGF expression might play a protective role in focal ischemia/reperfusion injury to the cerebrum.

[Vascular endothelial growth factor expression in focal cerebral ischemia/reperfusion in injury in rats] Publishing Authors By Initials

Y Xing,ZX Xu,J Mang,JL Qian,

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[Vascular endothelial growth factor expression in focal cerebral ischemia/reperfusion in injury in rats] Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Zhongguo wei zhong bing ji jiu yi xue = Chinese cr

VOLUME: 17

Page Numbers: 174-6

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ISSN: 1003-0603

DAY: 11

MONTH: Mar

YEAR: 2005

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LANGUAGE: chi

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AFFILIATION: Department of Neurology, China - Japan Union Hospital, Jilin University, Changchun, China.

Country: China

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MEDLINETA: Zhongguo Wei Zhong Bing Ji Jiu

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