A previously healthy 75-year-old man complained of persistent fever, headache, nausea, mild gait disturbance, memory disorder, and sporadic vesicular skin lesions. Viral meningoencephalitis was diagnosed, based on cerebrospinal fluid (CSF) analysis. Intensive CSF analysis suggested that the patient's illness was caused by varicella zoster virus (VZV). The patient recovered completely after treatment with intravenous acyclovir. VZV infection should be considered as a possible cause of central nervous system disease, even in an immunocompetent patient. VZV reactivation was strongly suspected because of the results of anti-VZV antibody evaluations in serum and CSF, although the skin lesions were not similar to those of herpes zoster.
Varicella zoster virus meningoencephalitis accompanied by sporadic skin lesions in an older immunocompetent adult. Publishing Authors By Initials
Varicella zoster virus meningoencephalitis accompanied by sporadic skin lesions in an older immunocompetent adult. Journal Published:
PUBLICATION TYPE: Journal Article
Journal: Journal of infection and chemotherapy : official j
VOLUME: 13
Page Numbers: 270-2
Journal Abbreviation: J. Infect. Chemother.
ISSN: 1341-321X
DAY: 27
MONTH: 08
YEAR: 2007
Varicella zoster virus meningoencephalitis accompanied by sporadic skin lesions in an older immunocompetent adult. Information
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LANGUAGE: eng
NlmUniqueID: 9608375
Varicella zoster virus meningoencephalitis accompanied by sporadic skin lesions in an older immunocompetent adult. Keywords Mesh Terms:
KEYWORDS: Skin Diseases
MESH TERMS: virology
Chemical & Substance for Abstract: Varicella zoster virus meningoencephalitis accompanied by sporadic skin lesions in an older immunocompetent adult. Information
Substance Name: Acyclovir
Registry Number: 59277-89-3
Grant and Affiliation Information for Varicella zoster virus meningoencephalitis accompanied by sporadic skin lesions in an older immunocompetent adult.
AFFILIATION: Department of Internal Medicine, Jusendo General Hospital, 1-8-16 Ekimae, Koriyama, Fukushima 963-8585, Japan. kota_sugisaki@ryumachi-jp.com
Country: Japan
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MEDLINETA: J Infect Chemother
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