[Value of blinded sampling methods in the pathogenic diagnosis of ventilator-associated pneumonia]

[Value of blinded sampling methods in the pathogenic diagnosis of ventilator-associated pneumonia] Research Abstract Details 

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[Value of blinded sampling methods in the pathogenic diagnosis of ventilator-associated pneumonia] Abstract Text:

Shao-Hua Cai,Sen-Yang Yu,Jin-Chuan Zhang,Chang-Ting Liu,Gui-Sheng Qian,

OBJECTIVE: To evaluate the diagnostic value of blinded protected specimen brush and quantitative culture (BPSB-QC) in the pathogenic diagnosis of ventilator-associated pneumonia (VAP). METHODS: A prospective, self-controlled clinical trial was conducted during a 36-month period. QC of paired samples of BPSB and PSB via a fiberoptic bronchoscopy (FOB- PSB) in a total of 54 patients during 125 suspected episodes of VAP was compared. The sensitivity and accuracy, as well as the concordance between BPSB-QC and FOB-PSB-QC result in 48 patients with 106 episodes of VAP were assessed. Both BPSB-QC and FOB-PSB-QC greater than 103 cfu/ml (positive cutoff) was considered diagnostic of VAP. RESULTS: Forty-eight patients with 106 episodes were considered to have VAP (84.8%). The accuracy of BPSB-QC and FOB-PSB-QC were 80.8% (101/125) and 83.2% (104/125), respectively. The rate of complete concordant results was high (75.2%) for BPSB-QC and FOB-PSB-QC. The pathogenic diagnostic agreement between the two techniques was 84.8% (106/125). There were no significant differences with regard to site of pneumonia and positive diagnostic rate between the two techniques. CONCLUSION: BPSB-QC has similar accuracy and same feasibility compared with FOB-PSB-QC which was commonly primarily used in the pathogenic diagnosis of VAP, and that its use is substantially simpler, safe and cost saving, especially when FOB technique is not available.

[Value of blinded sampling methods in the pathogenic diagnosis of ventilator-associated pneumonia] Publishing Authors By Initials

SH Cai,SY Yu,JC Zhang,CT Liu,GS Qian,

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[Value of blinded sampling methods in the pathogenic diagnosis of ventilator-associated pneumonia] Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Zhongguo wei zhong bing ji jiu yi xue = Chinese cr

VOLUME: 16

Page Numbers: 599-602

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ISSN: 1003-0603

DAY: 5

MONTH: Oct

YEAR: 2004

[Value of blinded sampling methods in the pathogenic diagnosis of ventilator-associated pneumonia] Information

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LANGUAGE: chi

NlmUniqueID: 9887521

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Grant and Affiliation Information for [Value of blinded sampling methods in the pathogenic diagnosis of ventilator-associated pneumonia]

AFFILIATION: Department of Geriatric-Respriatory, General Hospital of PLA, Beijing 100853, China. caish@301hospital.com.cn

Country: China

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MEDLINETA: Zhongguo Wei Zhong Bing Ji Jiu

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