Valence and salience contribute to nucleus accumbens activation.

Valence and salience contribute to nucleus accumbens activation. Research Abstract Details 

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Valence and salience contribute to nucleus accumbens activation. Abstract Text:

Jeffrey C Cooper,Brian Knutson,Jeffrey C Cooper,Brian Knutson,Jeffrey C Cooper,Brian Knutson,

Different accounts of nucleus accumbens (NAcc) function have emphasized its role in representing either valence or salience during incentive anticipation. In an event-related FMRI experiment, we independently manipulated valence and salience by cuing participants to anticipate certain and uncertain monetary gains and losses. NAcc activation correlated with both valence and salience. On trials with certain outcomes, NAcc activation increased for anticipated gains and decreased for anticipated losses. On trials with uncertain outcomes, NAcc activation increased for both anticipated gains and losses but did not differ between them. These findings suggest that NAcc activation separately represents both valence and salience, consistent with its hypothesized role in appetitive motivation.

Valence and salience contribute to nucleus accumbens activation. Publishing Authors By Initials

JC Cooper,B Knutson,JC Cooper,B Knutson,JC Cooper,B Knutson,

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Valence and salience contribute to nucleus accumbens activation. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: NeuroImage

VOLUME: 39

Page Numbers: 538-47

Journal Abbreviation: Neuroimage

ISSN: 1053-8119

DAY: 23

MONTH: 08

YEAR: 2007

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LANGUAGE: eng

NlmUniqueID: 9215515

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AFFILIATION: Department of Psychology, Jordan Hall, 450 Serra Mall, Stanford, CA 94305, USA.

Country: United States

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MEDLINETA: Neuroimage

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