Utility of high-dose contrast enhancement for detecting recurrent herniated intervertebral disks.

Utility of high-dose contrast enhancement for detecting recurrent herniated intervertebral disks. Research Abstract Details 

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Utility of high-dose contrast enhancement for detecting recurrent herniated intervertebral disks. Abstract Text:

C Nguyen,H An,K C Ho,V M Haughton,T Hasegawa,

PURPOSE: To study the utility of high-dose contrast enhancement in the detection of recurrent herniated disk fragments. METHODS: Recurrent herniated disks were modeled in nine dogs by placing a fragment of normal autologous disk tissue in the epidural space at laminectomy. MR was performed at 30, 60, and 90 days with 0.3 mmol/kg of gadoteridol and repeated 24 hours later with 0.1 mmol/kg of gadopentetate dimeglumine. Contrast enhancement in the disk and scar tissue was measured and conspicuousness of the disk fragments assessed. RESULTS: In 70% of the animals, disk fragments were more conspicuous with the larger dose of contrast medium than with the smaller dose. In 30% of animals the conspicuousness was approximately equal. Contrast between disk fragment and scar decreased with time elapsed since surgery, with time elapsed since contrast-medium injection, and with decreasing dose of contrast medium. CONCLUSION: In the experimental model, increased conspicuousness of disk fragments was achieved with the larger dose of contrast medium. A clinical study is needed to confirm that a contrast-medium dose of 0.3 mmol/kg improves detection of recurrent herniated disks over a dose of 0.1 mmol/kg.

Utility of high-dose contrast enhancement for detecting recurrent herniated intervertebral disks. Publishing Authors By Initials

C Nguyen,H An,KC Ho,VM Haughton,T Hasegawa,

For similar pathological conditions, signs and symptoms: pathologic processes: disease attributes: recurrence research abstracts see: pathological conditions, signs and symptoms: pathologic processes: disease attributes: recurrence research

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Utility of high-dose contrast enhancement for detecting recurrent herniated intervertebral disks. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: AJNR. American journal of neuroradiology

VOLUME: 15

Page Numbers: 1291-7

Journal Abbreviation:

ISSN: 0195-6108

DAY: 14

MONTH: Aug

YEAR: 1994

Utility of high-dose contrast enhancement for detecting recurrent herniated intervertebral disks. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 8003708

Utility of high-dose contrast enhancement for detecting recurrent herniated intervertebral disks. Keywords Mesh Terms:

KEYWORDS: Recurrence

MESH TERMS: diagnosis

Chemical & Substance for Abstract: Utility of high-dose contrast enhancement for detecting recurrent herniated intervertebral disks. Information

Substance Name: Gadolinium DTPA

Registry Number: 80529-93-7

Grant and Affiliation Information for Utility of high-dose contrast enhancement for detecting recurrent herniated intervertebral disks.

AFFILIATION: Department of Radiology, Medical College of Wisconsin, Milwaukee.

Country: UNITED STATES

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MEDLINETA: AJNR Am J Neuroradiol

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