Use of 120-nm deep channels for liquid chromatographic separations. Abstract Text:
The present study reports on the exploration of the separation speed limits of RPLC chromatography in open-tubular channels. Applying the shear-driven chromatography principle in a 120-nm deep open channel, and using an improved detection set-up, the separation of three coumarin dyes was detectable 8mm downstream of the injection point. At this distance, separation efficiencies of N=17,900-24,100 plates were obtained at a velocity of 10mms(-1), corresponding to a plate generation velocity of 21,100 to 28,300 plates per second for the most and least retained component, respectively.
Use of 120-nm deep channels for liquid chromatographic separations. Publishing Authors By Initials