Unstable angina and non-ST elevation acute coronary syndrome: epidemiology and current management in Japan (Japan Multicenter Investigation for Cardiovascular Disease-D (JMIC-D) Committee).

Unstable angina and non-ST elevation acute coronary syndrome: epidemiology and current management in Japan (Japan Multicenter Investigation for Cardiovascular Disease-D (JMIC-D) Committee). Research Abstract Details 

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Unstable angina and non-ST elevation acute coronary syndrome: epidemiology and current management in Japan (Japan Multicenter Investigation for Cardiovascular Disease-D (JMIC-D) Committee). Abstract Text:

Yoshiki Yui,Atsushi Hirayama,Hiroshi Nonogi,Kazuo Kimura,Kazuhisa Kodama,Saichi Hosoda,Chuichi Kawai,Yoshiki Yui,Atsushi Hirayama,Hiroshi Nonogi,Kazuo Kimura,Kazuhisa Kodama,Saichi Hosoda,Chuichi Kawai,

BACKGROUND: A multicenter study was conducted to assess the current medical management of unstable angina (UA) and non-ST-elevation acute coronary syndrome in Japan. METHODS AND RESULTS: This study presents the results of a nationwide questionnaire survey of 770 sites and a case report investigation performed at 20 sites. The questionnaire survey revealed that the number of acute myocardial infarction (AMI) patients treated annually was 1.56-fold greater than the number of UA patients. Non-ST-elevation AMI accounted for 17% of all patients with AMI. Analysis of case reports for 885 UA patients showed extensive use of invasive treatment. In the UA patients, the cumulative incidence of a composite endpoint (all-cause mortality, AMI, and urgent coronary revascularization) was 2% at 1 month and 9% at 6 months. Stratified analysis with respect to the composite endpoint through 6 months showed a significantly lower incidence in patients treated with a calcium-channel blocker than in patients not treated with a calcium-channel blocker. CONCLUSIONS: In Japan, fewer patients are hospitalized annually for treatment of UA than for AMI. The largest percentage of UA patients had Braunwald class III disease. Non-ST-elevation AMI is managed in Japan according to the principle of early invasive treatment, resembling the treatment for ST-elevation AMI. The outcome of treatment is better for Japanese UA patients than for Japanese AMI patients.

Unstable angina and non-ST elevation acute coronary syndrome: epidemiology and current management in Japan (Japan Multicenter Investigation for Cardiovascular Disease-D (JMIC-D) Committee). Publishing Authors By Initials

Y Yui,A Hirayama,H Nonogi,K Kimura,K Kodama,S Hosoda,C Kawai,Y Yui,A Hirayama,H Nonogi,K Kimura,K Kodama,S Hosoda,C Kawai,

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Unstable angina and non-ST elevation acute coronary syndrome: epidemiology and current management in Japan (Japan Multicenter Investigation for Cardiovascular Disease-D (JMIC-D) Committee). Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Circulation journal : official journal of the Japa

VOLUME: 71

Page Numbers: 1335-47

Journal Abbreviation: Circ. J.

ISSN: 1346-9843

DAY: 27

MONTH: Sep

YEAR: 2007

Unstable angina and non-ST elevation acute coronary syndrome: epidemiology and current management in Japan (Japan Multicenter Investigation for Cardiovascular Disease-D (JMIC-D) Committee). Information

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LANGUAGE: eng

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AFFILIATION: Department of Cardiovascular Medicine, Kyoto University Hospital, Kyoto, Japan. yoshiki@kuhp.kyoto-u.ac.jp

Country: Japan

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