Unintended benefits of immunosupression on autoimmune disease due to chemoradiation therapy for head and neck cancer.

Unintended benefits of immunosupression on autoimmune disease due to chemoradiation therapy for head and neck cancer. Research Abstract Details 

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Unintended benefits of immunosupression on autoimmune disease due to chemoradiation therapy for head and neck cancer. Abstract Text:

Mohammed Iqbal Syed,Louise J Clark,Roger D Sturrock,Mohammed Iqbal Syed,Louise J Clark,Roger D Sturrock,Mohammed Iqbal Syed,Louise J Clark,Roger D Sturrock,

The immune system is an important factor in the host's defenses against cancer. Immunosupression by radiation and/or chemotherapy is often associated with systemic and hematologic complications, opportunistic infections, and the development of malignancies, but immunosupression can also have beneficial effects, which are sometimes incidental. We report 2 patients with autoimmune diseases where immunosupression had beneficial effects. The first case is about a patient with carcinoma of the tonsil, with severe rheumatoid arthritis, who was treated with chemoradiation, which resulted in remission of his arthritis. The second case is about a patient with severe atopic eczema who was on long-term treatment with psoralen and ultraviolet A radiation and azathioprine; the patient developed metastatic carcinoma of the lip, which was treated with surgery and radiation that resulted in complete remission of his eczema.

Unintended benefits of immunosupression on autoimmune disease due to chemoradiation therapy for head and neck cancer. Publishing Authors By Initials

MI Syed,LJ Clark,RD Sturrock,MI Syed,LJ Clark,RD Sturrock,MI Syed,LJ Clark,RD Sturrock,

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MEDLINE DATE: 2008 Jan-Feb

Unintended benefits of immunosupression on autoimmune disease due to chemoradiation therapy for head and neck cancer. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: American journal of otolaryngology

VOLUME: 29

Page Numbers: 63-5

Journal Abbreviation: Am J Otolaryngol

ISSN: 0196-0709

DAY: 6

MONTH: 12

YEAR: 2007

Unintended benefits of immunosupression on autoimmune disease due to chemoradiation therapy for head and neck cancer. Information

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LANGUAGE: eng

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Grant and Affiliation Information for Unintended benefits of immunosupression on autoimmune disease due to chemoradiation therapy for head and neck cancer.

AFFILIATION: Royal Alexandra Hospital, Greater Glasgow & Clyde Hospitals NHS Trust, Glasgow, UK. iqbalms@hotmail.com

Country: United States

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MEDLINETA: Am J Otolaryngol

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