Unexpected case of aplastic anemia in a patient with glioblastoma multiforme treated with Temozolomide.

Unexpected case of aplastic anemia in a patient with glioblastoma multiforme treated with Temozolomide. Research Abstract Details 

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Unexpected case of aplastic anemia in a patient with glioblastoma multiforme treated with Temozolomide. Abstract Text:

Rakesh Jalali,Pritanjali Singh,Hari Menon,Sumeet Gujral,

We report the case of a 30-year-old woman with glioblastoma multiforme (GBM) treated with surgery followed by concomitant Temozolomide (TMZ) and external beam radiation, which she tolerated well without any interruptions. However, when she was being evaluated for adjuvant Temozolomide, she developed progressive decline in leukocyte counts and platelet counts and subsequently, febrile neutropenia with bleeding manifestations. A bone marrow aspiration and biopsy done showed a gross hypocellular bone marrow with very few erythriod and myeloid cells and no suggestion of progenitor cells, consistent with aplastic anemia.

Unexpected case of aplastic anemia in a patient with glioblastoma multiforme treated with Temozolomide. Publishing Authors By Initials

R Jalali,P Singh,H Menon,S Gujral,

For similar bacterial infections and mycoses: infection: sepsis research abstracts see: bacterial infections and mycoses: infection: sepsis research

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Unexpected case of aplastic anemia in a patient with glioblastoma multiforme treated with Temozolomide. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of neuro-oncology

VOLUME: 85

Page Numbers: 105-7

Journal Abbreviation: J. Neurooncol.

ISSN: 0167-594X

DAY: 16

MONTH: 05

YEAR: 2007

Unexpected case of aplastic anemia in a patient with glioblastoma multiforme treated with Temozolomide. Information

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LANGUAGE: eng

NlmUniqueID: 8309335

Unexpected case of aplastic anemia in a patient with glioblastoma multiforme treated with Temozolomide. Keywords Mesh Terms:

KEYWORDS: Sepsis

MESH TERMS: complications

Chemical & Substance for Abstract: Unexpected case of aplastic anemia in a patient with glioblastoma multiforme treated with Temozolomide. Information

Substance Name: temozolomide

Registry Number: 85622-93-1

Grant and Affiliation Information for Unexpected case of aplastic anemia in a patient with glioblastoma multiforme treated with Temozolomide.

AFFILIATION: Department of Radiation Oncology, 116 Tata Memorial Hospital, Parel, Mumbai 400 012, India. rjalali@medscape.com

Country: Netherlands

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MEDLINETA: J Neurooncol

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