It has been known that peripheral adverse event is caused by peripheral antimuscarinic action, from hyoscine butylbromide (Buscopan; Boehringer Ingelheim, Germany) used as a premedication for endoscopy. However, symptoms or signs associated with the central nervous system are rarely reported in the field of anesthesiology and peripartum labor. This central anticholinergic syndrome is likely caused by blockade of muscarinic cholinergic receptors in the central nervous system. There is no report on Buscopan-induced central anticholinergic syndrome in endoscopy room so far. Three middle-aged females unexpectedly suffered from anterograde amnesia after intramuscular injection of hyoscine butylbromide as an antispasmodic premedication for endoscopy at our endoscopy unit in the Health Promotion Center.
Unexpected anterograde amnesia associated with Buscopan used as a predmedication for endocscopy. Publishing Authors By Initials
Unexpected anterograde amnesia associated with Buscopan used as a predmedication for endocscopy. Journal Published:
PUBLICATION TYPE: Journal Article
Journal: World journal of gastroenterology : WJG
VOLUME: 13
Page Numbers: 3895-6
Journal Abbreviation: World J. Gastroenterol.
ISSN: 1007-9327
DAY: 28
MONTH: Jul
YEAR: 2007
Unexpected anterograde amnesia associated with Buscopan used as a predmedication for endocscopy. Information
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LANGUAGE: eng
NlmUniqueID: 100883448
Unexpected anterograde amnesia associated with Buscopan used as a predmedication for endocscopy. Keywords Mesh Terms:
KEYWORDS: Premedication
MESH TERMS: adverse effects
Chemical & Substance for Abstract: Unexpected anterograde amnesia associated with Buscopan used as a predmedication for endocscopy. Information
Substance Name: Butylscopolammonium Bromide
Registry Number: 149-64-4
Grant and Affiliation Information for Unexpected anterograde amnesia associated with Buscopan used as a predmedication for endocscopy.
AFFILIATION: Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Irwon-dong 50, Gangnam-gu, Seoul 135-710, Korea.
Country: China
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MEDLINETA: World J Gastroenterol
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