Ultraviolet-induced acantholysis in pemphigus.

Ultraviolet-induced acantholysis in pemphigus. Research Abstract Details 

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Ultraviolet-induced acantholysis in pemphigus. Abstract Text:

Ultraviolet irradiation produced an acantholytic phenomenon in normal skin of seven patients with pemphigus foliaceus. In six of the seven patients, this reaction was manifested by a positive Nikolsky sign and was confirmed by biopsy in four. Friction alone, infrared irradiation, occlusive dressing, and a rubefacient failed to produce a similar reaction. The thermal burn in the skin of patients having pemphigus was of subepidermal type. Ultraviolet-induced acantholysis was inhibited by chloroquine phosphate, taken orally, in the two patients tested. Prednisone had no such effect. It is concluded that ultraviolet light is a major aggravating stimulus for pemphigus foliaceus.

Ultraviolet-induced acantholysis in pemphigus. Publishing Authors By Initials

For similar environment and public health: environment: meteorological factors: atmosphere: weather: sunlight: ultraviolet rays research abstracts see: environment and public health: environment: meteorological factors: atmosphere: weather: sunlight: ultraviolet rays research

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Ultraviolet-induced acantholysis in pemphigus. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Archives of dermatology

VOLUME: 92

Page Numbers: 7-13

Journal Abbreviation: Arch Dermatol

ISSN: 0003-987X

DAY: 17

MONTH: Jul

YEAR: 1965

Ultraviolet-induced acantholysis in pemphigus. Information

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LANGUAGE: eng

NlmUniqueID: 372433

Ultraviolet-induced acantholysis in pemphigus. Keywords Mesh Terms:

KEYWORDS: Ultraviolet Rays

MESH TERMS: adverse effects

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Grant and Affiliation Information for Ultraviolet-induced acantholysis in pemphigus.

AFFILIATION: Section of Dermatology, Mayo Clinic, Mayo Foundation, Rochester, Minn., USA.

Country: United States

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MEDLINETA: Arch Dermatol

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