Two new phenolic constituents of Humulus japonicus and their cytotoxicity test in vitro.

Two new phenolic constituents of Humulus japonicus and their cytotoxicity test in vitro. Research Abstract Details 

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Two new phenolic constituents of Humulus japonicus and their cytotoxicity test in vitro. Abstract Text:

Byung Chul Yu,Min Cheol Yang,Kyu Ha Lee,Ki Hyun Kim,Sang Un Choi,Kang Ro Lee,Byung Chul Yu,Min Cheol Yang,Kyu Ha Lee,Ki Hyun Kim,Sang Un Choi,Kang Ro Lee,Byung Chul Yu,Min Cheol Yang,Kyu Ha Lee,Ki Hyun Kim,Sang Un Choi,Kang Ro Lee,

Two new phenolic constituents (4 and 6), together with four known constituents, methyl ferulate (1), eugenyl-beta-D-glucopyranoside (2), apigenin-7-O-beta-D-glucopyranoside (3), and (E)-resveratrol-3-O-beta-D-glucopyranoside (5) were isolated from the MeOH extract of the aerial part sof Humulus japonicus. The structures of the new compounds were determined by spectroscopic methods to be divarin-3-O-beta-glucopyranoside (4), and lariciresinol-9-O-beta-xylopyranoside (6). Compounds 1 and 3 exhibited moderate cytotoxicity against two human cancer cell lines (SK-OV-3 and HCT15) with ED50 values ranging from 8.84 to 8.79 microM.

Two new phenolic constituents of Humulus japonicus and their cytotoxicity test in vitro. Publishing Authors By Initials

BC Yu,MC Yang,KH Lee,KH Kim,SU Choi,KR Lee,BC Yu,MC Yang,KH Lee,KH Kim,SU Choi,KR Lee,BC Yu,MC Yang,KH Lee,KH Kim,SU Choi,KR Lee,

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Two new phenolic constituents of Humulus japonicus and their cytotoxicity test in vitro. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Archives of pharmacal research

VOLUME: 30

Page Numbers: 1471-5

Journal Abbreviation: Arch. Pharm. Res.

ISSN: 0253-6269

DAY: 19

MONTH: Nov

YEAR: 2007

Two new phenolic constituents of Humulus japonicus and their cytotoxicity test in vitro. Information

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LANGUAGE: eng

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Grant and Affiliation Information for Two new phenolic constituents of Humulus japonicus and their cytotoxicity test in vitro.

AFFILIATION: Natural Products Laboratory, College of Pharmacy, Sungkyunkwan University, Suwon 440-746, Korea.

Country: Korea (South)

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MEDLINETA: Arch Pharm Res

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