Twinrix is the only licensed vaccine that provides dual protection against infection with hepatitis A virus (HAV) and hepatitis B virus (HBV). The standard vaccination schedule for Twinrix is 0, 1 and 6 months. However, many high-risk populations, such as injecting drug users (IDUs), do not complete the vaccination series and, thus, do not acquire sufficient immunity against HAV and HBV. Twinrix can be administered using an accelerated vaccination schedule of 0, 7 and 21 days, with a booster recommended at 12 months. This manuscript reviews the available literature on vaccinating IDUs against HAV and HBV. The authors conclude that there is insufficient evidence regarding whether the accelerated Twinrix HAV/HBV vaccination schedule would yield a greater number of IDUs protected against both HAV and HBV.
Twinrix vaccination schedules among injecting drug users. Publishing Authors By Initials
Twinrix vaccination schedules among injecting drug users. Journal Published:
PUBLICATION TYPE: Research Support, U.S. Gov't,
Journal: Expert opinion on biological therapy
VOLUME: 7
Page Numbers: 379-89
Journal Abbreviation:
ISSN: 1744-7682
DAY: 3
MONTH: Mar
YEAR: 2007
Twinrix vaccination schedules among injecting drug users. Information
Number of References:
LANGUAGE: eng
NlmUniqueID: 101125414
Twinrix vaccination schedules among injecting drug users. Keywords Mesh Terms:
KEYWORDS: Vaccines, Combined
MESH TERMS: administration & dosage
Chemical & Substance for Abstract: Twinrix vaccination schedules among injecting drug users. Information
Substance Name: twinrix
Registry Number: 0
Grant and Affiliation Information for Twinrix vaccination schedules among injecting drug users.
AFFILIATION: Brown Medical School, Providence, Rhode Island, USA, 2The Miriam Hospital, 164 Summit Ave, Providence, RI 02906, USA. nzaller@lifespan.org
Country: England
AGENCY: United States CSAT
GRANT: TI15870
ACRONYM: TI
MEDLINETA: Expert Opin Biol Ther
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