Tuning gene expression to changing environments: from rapid responses to evolutionary adaptation.

Tuning gene expression to changing environments: from rapid responses to evolutionary adaptation. Research Abstract Details 

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Tuning gene expression to changing environments: from rapid responses to evolutionary adaptation. Abstract Text:

Organisms are constantly exposed to a wide range of environmental changes, including both short-term changes during their lifetime and longer-term changes across generations. Stress-related gene expression programmes, characterized by distinct transcriptional mechanisms and high levels of noise in their expression patterns, need to be balanced with growth-related gene expression programmes. A range of recent studies give fascinating insight into cellular strategies for keeping gene expression in tune with physiological needs dictated by the environment, promoting adaptation to both short- and long-term environmental changes. Not only do organisms show great resilience to external challenges, but emerging data suggest that they also exploit these challenges to fuel phenotypic variation and evolutionary innovation.

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Tuning gene expression to changing environments: from rapid responses to evolutionary adaptation. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Nature reviews. Genetics

VOLUME: 9

Page Numbers: 583-93

Journal Abbreviation: Nat. Rev. Genet.

ISSN: 1471-0064

DAY: 18

MONTH: Aug

YEAR: 2008

Tuning gene expression to changing environments: from rapid responses to evolutionary adaptation. Information

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LANGUAGE: eng

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Grant and Affiliation Information for Tuning gene expression to changing environments: from rapid responses to evolutionary adaptation.

AFFILIATION: Department of Genetics, Evolution and Environment, UCL Cancer Institute, University College London, London WC1E 6BT, UK.

Country: England

AGENCY: United Kingdom Cancer Res

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MEDLINETA: Nat Rev Genet

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