TrkA expression in mouse olfactory tract following axotomy of olfactory nerves.

TrkA expression in mouse olfactory tract following axotomy of olfactory nerves. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

TrkA expression in mouse olfactory tract following axotomy of olfactory nerves. Abstract Text:

T Miwa,I Horikawa,N Uramoto,T Ishimaru,K Yamamoto,M Furukawa,T Kato,T Moriizumi,

The olfactory bulb is one of the brain regions that synthesizes the nerve growth factor (NGF). Functional roles of the bulbar NGF remain to be determined. The aim of the present study was, using an antibody specific to the high-affinity NGF receptor (trkA), to examine immunohistochemically the distribution of the NGF receptor in the mouse olfactory tract, under normal conditions and during regenerative processes. In normal mouse olfactory epithelia, trkA immunoreactive cell bodies were only seen in basal cells. Cell bodies of olfactory receptor cells did not express trkA immunoreactivity, but their neuronal processes (olfactory nerve fibres and bundles in the olfactory mucosa and the olfactory bulb) displayed trkA immunoreactivity. After axotomy of olfactory nerves, regenerating olfactory cells (basal cells and olfactory receptor cells) expressed trkA immunoreactivity in intramucosal and intrabulbar neuronal processes of olfactory receptor cells. These results suggest involvement of the bulbar NGF in the process of synaptogenesis and/or regeneration of the olfactory nervous system.

TrkA expression in mouse olfactory tract following axotomy of olfactory nerves. Publishing Authors By Initials

T Miwa,I Horikawa,N Uramoto,T Ishimaru,K Yamamoto,M Furukawa,T Kato,T Moriizumi,

For similar natural sciences: time: time factors research abstracts see: natural sciences: time: time factors research

PUBMED ID PMID:

MEDLINE DATE:

TrkA expression in mouse olfactory tract following axotomy of olfactory nerves. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Acta oto-laryngologica. Supplementum

VOLUME: 539

Page Numbers: 79-82

Journal Abbreviation:

ISSN: 0365-5237

DAY: 13

MONTH: 02

YEAR: 1998

TrkA expression in mouse olfactory tract following axotomy of olfactory nerves. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 370355

TrkA expression in mouse olfactory tract following axotomy of olfactory nerves. Keywords Mesh Terms:

KEYWORDS: Time Factors

MESH TERMS: physiology

Chemical & Substance for Abstract: TrkA expression in mouse olfactory tract following axotomy of olfactory nerves. Information

Substance Name: Receptor, trkA

Registry Number: EC 2.7.1.112

Grant and Affiliation Information for TrkA expression in mouse olfactory tract following axotomy of olfactory nerves.

AFFILIATION: Department of Otorhinolaryngology, School of Medicine, Kanazawa University, Japan.

Country: NORWAY

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Acta Otolaryngol Suppl

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

TrkA expression in mouse olfactory tract following axotomy of olfactory nerves Related Publications

• A transverse ligament located anterosuperiorly in the lower orbital fat space restricts lower eyelid retraction in the Mongoloid eye.
• Adult neurogenesis and gliogenesis in the rat olfactory nervous system.
• Efferent projections from the striatal patch compartment: anterograde degeneration after selective ablation of neurons expressing mu-opioid receptor in rats.
• Neural plasticity of neonatal hypoglossal nerve for effective suckling.
• Olfactory impairment and Parkinson's disease-like symptoms observed in the common marmoset following administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
• Precise measurement of SAW velocity using SAW delay line.
• Proliferating cell populations in experimentally-induced hydrocephalus in developing rats.
• TrkA expression in mouse olfactory tract following axotomy of olfactory nerves.
• Tyrosine hydroxylase-immunoreactive fibers in the human vagus nerve.