Tributyltin causes abnormal development in embryos of medaka, Oryzias latipes.

Tributyltin causes abnormal development in embryos of medaka, Oryzias latipes. Research Abstract Details 

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Tributyltin causes abnormal development in embryos of medaka, Oryzias latipes. Abstract Text:

Takeshi Hano,Yuji Oshima,Sang Gyoon Kim,Hina Satone,Yumi Oba,Takeshi Kitano,Suguru Inoue,Yohei Shimasaki,Tsuneo Honjo,Takeshi Hano,Yuji Oshima,Sang Gyoon Kim,Hina Satone,Yumi Oba,Takeshi Kitano,Suguru Inoue,Yohei Shimasaki,Tsuneo Honjo,Takeshi Hano,Yuji Oshima,Sang Gyoon Kim,Hina Satone,Yumi Oba,Takeshi Kitano,Suguru Inoue,Yohei Shimasaki,Tsuneo Honjo,

We examined the effects of tributyltin (TBT) on embryonic development, hatching success and sexual differentiation in Japanese medaka (Oryzias latipes). Embryos (within 8h after fertilization) were exposed to TBT in ovo via nanoinjection at concentrations of 0 (control), 0.16, 0.80, 3.96, 19.2 and 82.1ng/egg. Embryonic survival, development and hatching were observed. Hatched fry were reared until 60 days when they sexually matured, and sexual differentiation was also examined by accordance of genetic and phenotypic sex, based on existence of DMY (a male determining gene in medaka) and secondary sex characteristics. As results, TBT caused a concentration-dependent mortality and impaired the embryonic development. However, no masculinization was detected at 60dph medaka adults. Lowest observed effective concentration for inducing abnormal embryonic development was estimated to 0.16ng/egg (ca. 160ng/g egg).

Tributyltin causes abnormal development in embryos of medaka, Oryzias latipes. Publishing Authors By Initials

T Hano,Y Oshima,SG Kim,H Satone,Y Oba,T Kitano,S Inoue,Y Shimasaki,T Honjo,T Hano,Y Oshima,SG Kim,H Satone,Y Oba,T Kitano,S Inoue,Y Shimasaki,T Honjo,T Hano,Y Oshima,SG Kim,H Satone,Y Oba,T Kitano,S Inoue,Y Shimasaki,T Honjo,

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Tributyltin causes abnormal development in embryos of medaka, Oryzias latipes. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Chemosphere

VOLUME: 69

Page Numbers: 927-33

Journal Abbreviation: Chemosphere

ISSN: 0045-6535

DAY: 7

MONTH: 08

YEAR: 2007

Tributyltin causes abnormal development in embryos of medaka, Oryzias latipes. Information

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LANGUAGE: eng

NlmUniqueID: 320657

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AFFILIATION: Division of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, Hakozaki 6-10-1, Higashi-ku, Fukuoka 812-8581, Japan.

Country: England

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MEDLINETA: Chemosphere

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