Trends in incidence of esophageal and gastric cardia cancer in high-risk areas in China.

Trends in incidence of esophageal and gastric cardia cancer in high-risk areas in China. Research Abstract Details 

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Trends in incidence of esophageal and gastric cardia cancer in high-risk areas in China. Abstract Text:

Yu-Tong He,Jun Hou,Zhi-Feng Chen,Cui-Yun Qiao,Guo-Hui Song,Fan-Shu Meng,Hong-Xin Jin,Chao Chen,

Incidence rates have risen for gastric cardia adenocarcinoma, whereas rates have remained stable for esophageal squamous cell carcinoma in many western countries. The aim of this study was to describe and analyze trends in incidence rates for esophageal cancer and gastric cardia cancer in Cixian county, which is one of the high-risk areas for esophageal cancer in China as well as in the world. The data were obtained from the Cixian Cancer Registry, which is a population-based registry. All the data were checked and analyzed using SPSS 11.5. Between the years 1988 and 2003 there were 11,183 cases of esophageal cancer in the county. The age-standardized incidence rate was 168.55 per 100,000. In 1988, the age-standardized incidence rate for male patients was 250.76/100,000; it declined to 160.05/100,000 in 2003, representing a decrease of 36.2%. The age-standardized incidence rate for female patients was 153.86/100,000 in 1988; it declined to 82.55/100,000 in 2003, showing a decrease of 46.3%. A slight decreasing trend was observed during the period, with a yearly decrease of 3.61% in male patients and 3.39% in female patients. For gastric cardia cancer, there were 1654 cases from 1988 to 2003. The age-standardized incidence rate was 25.58 per 100,000. The age-standardized incidence rate for male patients was 13.75/100,000 in 1988; it increased to 28.55/100,000 in 2003, with a yearly increase of 7.65%. The age-standardized incidence rate for female patients was 7.12/100,000 in 1988; it increased to 12.91/100,000, with a yearly increase of 5.44%. A statistically significant increasing trend of gastric cardia cancer was observed during the study period. Cixian county is a geographical region with a very high incidence of esophageal cancer and cardia cancer. The trend in the incidence rates of esophageal cancer had decreased slightly; on the other hand, gastric cardia cancer showed a significantly increased trend in the last 16 years. Detailed epidemiological analyses of demographic trends and risk factors will help to guide future cancer control strategies.

Trends in incidence of esophageal and gastric cardia cancer in high-risk areas in China. Publishing Authors By Initials

YT He,J Hou,ZF Chen,CY Qiao,GH Song,FS Meng,HX Jin,C Chen,

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Trends in incidence of esophageal and gastric cardia cancer in high-risk areas in China. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: European journal of cancer prevention : the offici

VOLUME: 17

Page Numbers: 71-6

Journal Abbreviation: Eur. J. Cancer Prev.

ISSN: 1473-5709

DAY: 21

MONTH: Apr

YEAR: 2008

Trends in incidence of esophageal and gastric cardia cancer in high-risk areas in China. Information

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LANGUAGE: eng

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AFFILIATION: The Fourth Affiliated Hospital, Hebei Medical University, Hebei Cancer Institute, Shijiazhuang, China. hytong69@yahoo.com

Country: England

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MEDLINETA: Eur J Cancer Prev

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