Treatment of hepatocellular carcinoma by chemoembolization: evaluation with 3DFT MR imaging.

Treatment of hepatocellular carcinoma by chemoembolization: evaluation with 3DFT MR imaging. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Treatment of hepatocellular carcinoma by chemoembolization: evaluation with 3DFT MR imaging. Abstract Text:

T Murakami,H Nakamura,K Tsuda,K Nakanishi,S Hori,K Tomoda,T Mitani,T Kozuka,M Monden,K Wakasa,

OBJECTIVE. We evaluated the usefulness of an MR imaging technique that used dynamic three-dimensional Fourier transformation (3DFT) fast imaging with steady-state precession (FISP) with gadopentetate dimeglumine for detecting viable regions of hepatocellular carcinoma following transcatheter arterial chemoembolization with iodized oil (Lipiodol). Images obtained with the 3DFT FISP technique were directly correlated with hepatectomy specimens. SUBJECTS AND METHODS. Dynamic 3DFT FISP MR imaging was performed after transcatheter arterial chemoembolization and before partial hepatectomy in 10 patients with 10 tumors of hepatocellular carcinoma. Imaging parameters were 20/8/30 degrees (TR/TE/flip angle) with a slab thickness of 21-75 mm and seven or 15 partitions. 3DFT FISP images were obtained at the slice level where a tumor had been detected on T1- and/or T2-weighted spin-echo MR images before, just after (early phase), and 1 and 2 min after (late phase) IV administration of gadopentetate dimeglumine (0.1 mmol/kg). We directly compared the dynamic MR images of the 10 patients with the gross and microscopic findings. RESULTS. On early-phase images, tumors of hepatocellular carcinoma showed no enhancement in three patients and partial intense enhancement in seven. Viable regions of the tumor showed intense enhancement relative to the surrounding liver parenchyma in the early phase, whereas necrotic regions showed no enhancement in either the early or the late phase. Both viable and necrotic regions had lower signal intensities than did the surrounding liver parenchyma in the late phase. By using dynamic 3DFT MR imaging, we were able to accurately assess the effect of transcatheter arterial chemoembolization with iodized oil in nine of the 10 patients. However, in one patient in whom microscopically viable cells were seen in the capsule of the carcinoma, viable regions could not be detected with our technique. CONCLUSION. Dynamic 3DFT MR imaging was useful in differentiating viable regions of hepatocellular carcinoma from necrotic regions following transcatheter arterial chemoembolization with iodized oil.

Treatment of hepatocellular carcinoma by chemoembolization: evaluation with 3DFT MR imaging. Publishing Authors By Initials

T Murakami,H Nakamura,K Tsuda,K Nakanishi,S Hori,K Tomoda,T Mitani,T Kozuka,M Monden,K Wakasa,

For similar organic chemicals: amines: polyamines: pentetic acid research abstracts see: organic chemicals: amines: polyamines: pentetic acid research

PUBMED ID PMID:

MEDLINE DATE:

Treatment of hepatocellular carcinoma by chemoembolization: evaluation with 3DFT MR imaging. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: AJR. American journal of roentgenology

VOLUME: 160

Page Numbers: 295-9

Journal Abbreviation:

ISSN: 0361-803X

DAY: 15

MONTH: Feb

YEAR: 1993

Treatment of hepatocellular carcinoma by chemoembolization: evaluation with 3DFT MR imaging. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 7708173

Treatment of hepatocellular carcinoma by chemoembolization: evaluation with 3DFT MR imaging. Keywords Mesh Terms:

KEYWORDS: Pentetic Acid

MESH TERMS: diagnostic use

Chemical & Substance for Abstract: Treatment of hepatocellular carcinoma by chemoembolization: evaluation with 3DFT MR imaging. Information

Substance Name: Gadolinium DTPA

Registry Number: 80529-93-7

Grant and Affiliation Information for Treatment of hepatocellular carcinoma by chemoembolization: evaluation with 3DFT MR imaging.

AFFILIATION: Department of Radiology, Osaka University Medical School, Japan.

Country: UNITED STATES

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: AJR Am J Roentgenol

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Treatment of hepatocellular carcinoma by chemoembolization: evaluation with 3DFT MR imaging Related Publications

• A case of synovial sarcoma in the perivertebral space of the neck: clinical presentation, radiological findings and histopathological description.
• Anomalous Magnetic Field Effects on Photochemical Reactions in Ionic Liquid under Ultrahigh Fields of up to 28 T.
• Integrated metabolomic and transcriptomic analyses of high-tryptophan rice expressing a mutant anthranilate synthase alpha subunit.
• Intramasseteric schwannoma in a child.
• Lack of amyloid plaque formation in the central nervous system of a patient with Werner syndrome.
• Mutation of a rice gene encoding a phenylalanine biosynthetic enzyme results in accumulation of phenylalanine and tryptophan.
• Positron emission tomographic imaging of pleomorphic adenoma in the parotid gland.
• Pulmonary inverted Schneiderian papilloma causing high serum levels of carcinoembryonic antigen and squamous cell carcinoma-associated antigen: report of a case.
• Spindle cell carcinoma as a locally recurrent malignancy after surgery for early lingual squamous cell carcinoma.
• Squamous cell carcinoma as a rare entity of primary liver tumor with grave prognosis.
• The tryptophan pathway is involved in the defense responses of rice against pathogenic infection via serotonin production.
• Treatment of hepatocellular carcinoma by chemoembolization: evaluation with 3DFT MR imaging.