Transmission mode ion/ion proton transfer reactions in a linear ion trap.

Transmission mode ion/ion proton transfer reactions in a linear ion trap. Research Abstract Details 

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Transmission mode ion/ion proton transfer reactions in a linear ion trap. Abstract Text:

Xiaorong Liang,Scott A McLuckey,

A new method is described for effecting ion/ion proton transfer reactions that involves storage of analyte ions while oppositely charged ions are transmitted through the stored ion population. In this approach, the products are captured and stored in the linear ion trap for subsequent mass analysis. Charge reduction of multiply charged protein ions is used as an example to illustrate the analytical usefulness of this method. In another variation of the transmission mode ion/ion reaction approach, two charge inversion experiments, implemented by passing analyte ions through a population of multiply charged reagent ions in a LIT, are also demonstrated. A pulsed dual ion source approach coupled with a hybrid triple quadrupole/linear ion trap instrument was used to demonstrate these two methods. The results for ion/ion reactions implemented using these so-called "transmission mode" experiments were comparable to those acquired using the more conventional mutual storage mode, both in terms of efficiency and information content of the spectra. An advantage of transmission mode experiments compared with mutual storage mode experiments is that they do not require any specialized measures to be taken to enable the simultaneous storage of oppositely charged ions.

Transmission mode ion/ion proton transfer reactions in a linear ion trap. Publishing Authors By Initials

X Liang,SA McLuckey,

For similar proteins: ubiquitins: ubiquitin research abstracts see: proteins: ubiquitins: ubiquitin research

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MEDLINE DATE:

Transmission mode ion/ion proton transfer reactions in a linear ion trap. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Journal of the American Society for Mass Spectrome

VOLUME: 18

Page Numbers: 882-90

Journal Abbreviation:

ISSN: 1044-0305

DAY: 8

MONTH: 03

YEAR: 2007

Transmission mode ion/ion proton transfer reactions in a linear ion trap. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 9010412

Transmission mode ion/ion proton transfer reactions in a linear ion trap. Keywords Mesh Terms:

KEYWORDS: Ubiquitin

MESH TERMS: chemistry

Chemical & Substance for Abstract: Transmission mode ion/ion proton transfer reactions in a linear ion trap. Information

Substance Name: Bradykinin

Registry Number: 58-82-2

Grant and Affiliation Information for Transmission mode ion/ion proton transfer reactions in a linear ion trap.

AFFILIATION: Department of Chemistry, Purdue University, West Lafayette, Indiana 47907-2084, USA.

Country: United States

AGENCY: United States NIGMS

GRANT: R01 GM045372-12

ACRONYM: GM

MEDLINETA: J Am Soc Mass Spectrom

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