Toxinotypes of Clostridium perfringens isolated from sick and healthy avian species.

Toxinotypes of Clostridium perfringens isolated from sick and healthy avian species. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Toxinotypes of Clostridium perfringens isolated from sick and healthy avian species. Abstract Text:

Rocio Crespo,Derek J Fisher,H L Shivaprasad,Mariano E ,Francisco A Uzal,

Currently, the factors/toxins responsible for Clostridium perfringens-associated avian enteritis are not well understood. To assess whether specific C. perfringens' toxinotypes are associated with avian enteritis, the isolates of C. perfringens from 31 cases of avian necrotic or ulcerative enteritis submitted between 1997 and 2005 were selected for retrospective analysis using multiplex PCR. C. perfringens was isolated from chickens, turkeys, quail, and psittacines. The toxinotypes of isolates from diseased birds were compared against the toxinotype of 19 C. perfringens isolates from avian cases with no evidence of clostridial enteritis. All C. perfringens isolates were classified as type A regardless of species or disease history. Although many isolates (from all avian groups) had the gene encoding the C. perfirngens beta2 toxin, only 54% produced the toxin in vitro when measured using Western blot analysis. Surprisingly, a large number of healthy birds (90%) carried CPB2-producing isolates, whereas over half of the cpb2-positive isolates from diseased birds failed to produce CPB2. These data from this investigation do not suggest a causal relationship between beta2 toxin and necrotic enteritis in birds.

Toxinotypes of Clostridium perfringens isolated from sick and healthy avian species. Publishing Authors By Initials

R Crespo,DJ Fisher,HL Shivaprasad,ME ,FA Uzal,

For similar investigative techniques: epidemiologic methods: epidemiologic study characteristics as topic: epidemiologic studies: case-control studies: retrospective studies research abstracts see: investigative techniques: epidemiologic methods: epidemiologic study characteristics as topic: epidemiologic studies: case-control studies: retrospective studies research

PUBMED ID PMID:

MEDLINE DATE:

Toxinotypes of Clostridium perfringens isolated from sick and healthy avian species. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: Journal of veterinary diagnostic investigation : o

VOLUME: 19

Page Numbers: 329-33

Journal Abbreviation:

ISSN: 1040-6387

DAY: 3

MONTH: May

YEAR: 2007

Toxinotypes of Clostridium perfringens isolated from sick and healthy avian species. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 9011490

Toxinotypes of Clostridium perfringens isolated from sick and healthy avian species. Keywords Mesh Terms:

KEYWORDS: Retrospective Studies

MESH TERMS: veterinary

Chemical & Substance for Abstract: Toxinotypes of Clostridium perfringens isolated from sick and healthy avian species. Information

Substance Name: DNA, Bacterial

Registry Number: 0

Grant and Affiliation Information for Toxinotypes of Clostridium perfringens isolated from sick and healthy avian species.

AFFILIATION: California Animal Health and Food Safety Laboratory System, University of California Davis, Fresno Branch, 2789 South Orange Avenue, Fresno, CA 93725, USA. rmcrespo@ucdavis.edu

Country: United States

AGENCY: United States NIAID

GRANT: AI056177-03

ACRONYM: AI

MEDLINETA: J Vet Diagn Invest

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Toxinotypes of Clostridium perfringens isolated from sick and healthy avian species Related Publications

• An unusual metastatic site of tongue carcinoma: Shoulder muscles.
• Both epsilon-toxin and beta-toxin are important for the lethal properties of Clostridium perfringens type B isolates in the mouse intravenous injection model.
• Chemotherapy and cerebrovascular disease.
• Cluster of cases of malignant schwannoma in cattle.
• Development and application of an oral challenge mouse model for studying Clostridium perfringens type D infection.
• Effects of Clostridium perfringens Beta-Toxin on the Rabbit Small Intestine and Colon.
• Lethal effects of Clostridium perfringens epsilon toxin are potentiated by alpha and perfringolysin-O toxins in a mouse model.
• Lung, bone, skeletal muscles and cutaneous metastases from adenoid cystic carcinoma of the parotid gland: a case report and review of the literature.
• Necrotizing enterocolitis and death in a goat kid associated with enterotoxin (CPE)-producing Clostridium perfringens type A.
• Noncytotoxic Clostridium perfringens enterotoxin (CPE) variants localize CPE intestinal binding and demonstrate a relationship between CPE-induced cytotoxicity and enterotoxicity.
• Small cell carcinoma of the rectum; report of a case.
• Sudden death: A case report of hepatocellular carcinoma with tumor thrombus extending into the right atrium (LETTER TO THE EDITOR).
• Toxinotypes of Clostridium perfringens isolated from sick and healthy avian species.