Total synthesis of spiruchostatin B, a potent histone deacetylase inhibitor, from a microorganism.

Total synthesis of spiruchostatin B, a potent histone deacetylase inhibitor, from a microorganism. Research Abstract Details 

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Total synthesis of spiruchostatin B, a potent histone deacetylase inhibitor, from a microorganism. Abstract Text:

Toshiya Takizawa,Kazuhiro Watanabe,Koichi Narita,Takamasa Oguchi,Hideki Abe,Tadashi Katoh,

The first total synthesis of spiruchostatin B, a potent histone deacetylase inhibitor, was achieved in a convergent manner; the synthesis established stereochemistry at the C5'' position.

Total synthesis of spiruchostatin B, a potent histone deacetylase inhibitor, from a microorganism. Publishing Authors By Initials

T Takizawa,K Watanabe,K Narita,T Oguchi,H Abe,T Katoh,

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Total synthesis of spiruchostatin B, a potent histone deacetylase inhibitor, from a microorganism. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Chemical communications (Cambridge, England)

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Page Numbers: 1677-9

Journal Abbreviation: Chem. Commun. (Camb.)

ISSN: 1359-7345

DAY: 5

MONTH: 02

YEAR: 2008

Total synthesis of spiruchostatin B, a potent histone deacetylase inhibitor, from a microorganism. Information

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LANGUAGE: eng

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Grant and Affiliation Information for Total synthesis of spiruchostatin B, a potent histone deacetylase inhibitor, from a microorganism.

AFFILIATION: Laboratory of Synthetic Medicinal Chemistry, Department of Chemical Pharmaceutical Science, Tohoku Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai, 981-8558, Japan. katoh@tohoku-pharm.ac.jp.

Country: England

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MEDLINETA: Chem Commun (Camb)

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