Total synthesis of asimicin via highly stereoselective [3 + 2] annulation reactions of substituted allylsilanes.

Total synthesis of asimicin via highly stereoselective [3 + 2] annulation reactions of substituted allylsilanes. Research Abstract Details 

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Total synthesis of asimicin via highly stereoselective [3 + 2] annulation reactions of substituted allylsilanes. Abstract Text:

Jennifer M Tinsley,William R Roush,

A highly stereoselective total synthesis of (+)-asimicin (1) is reported. The synthesis features two chelate-controlled [3 + 2] annulation reactions-one of which (e.g., 2 + 3) constitutes a key, convergent fragment assembly step-that establish all of the stereochemistry of the bis-tetrahydrofuran unit of the natural product.

Total synthesis of asimicin via highly stereoselective [3 + 2] annulation reactions of substituted allylsilanes. Publishing Authors By Initials

JM Tinsley,WR Roush,

For similar natural sciences: chemistry: chemistry, organic: isomerism: stereoisomerism research abstracts see: natural sciences: chemistry: chemistry, organic: isomerism: stereoisomerism research

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Total synthesis of asimicin via highly stereoselective [3 + 2] annulation reactions of substituted allylsilanes. Journal Published:

PUBLICATION TYPE: Research Support, U.S. Gov't,

Journal: Journal of the American Chemical Society

VOLUME: 127

Page Numbers: 10818-9

Journal Abbreviation: J. Am. Chem. Soc.

ISSN: 0002-7863

DAY: 10

MONTH: Aug

YEAR: 2005

Total synthesis of asimicin via highly stereoselective [3 + 2] annulation reactions of substituted allylsilanes. Information

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LANGUAGE: eng

NlmUniqueID: 7503056

Total synthesis of asimicin via highly stereoselective [3 + 2] annulation reactions of substituted allylsilanes. Keywords Mesh Terms:

KEYWORDS: Stereoisomerism

MESH TERMS: chemistry

Chemical & Substance for Abstract: Total synthesis of asimicin via highly stereoselective [3 + 2] annulation reactions of substituted allylsilanes. Information

Substance Name: bullatacin

Registry Number: 102989-24-2

Grant and Affiliation Information for Total synthesis of asimicin via highly stereoselective [3 + 2] annulation reactions of substituted allylsilanes.

AFFILIATION: Department of Chemistry, University of Michigan, Ann Arbor, MI 48109-1055, USA.

Country: United States

AGENCY: United States NIGMS

GRANT: GM 38907

ACRONYM: GM

MEDLINETA: J Am Chem Soc

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