The total synthesis of (-)-scabronine G has been achieved in a concise manner from the (-)-Wieland-Miescher ketone. Scabronine G and its more potent methyl ester (also prepared) display activity as nonpeptidyl inducers of nerve growth factor production.
Total synthesis of (-)-scabronine G, an inducer of neurotrophic factor production. Publishing Authors By Initials
Total synthesis of (-)-scabronine G, an inducer of neurotrophic factor production. Journal Published:
PUBLICATION TYPE: Research Support, U.S. Gov't,
Journal: Journal of the American Chemical Society
VOLUME: 127
Page Numbers: 13514-5
Journal Abbreviation: J. Am. Chem. Soc.
ISSN: 0002-7863
DAY: 5
MONTH: Oct
YEAR: 2005
Total synthesis of (-)-scabronine G, an inducer of neurotrophic factor production. Information
Number of References:
LANGUAGE: eng
NlmUniqueID: 7503056
Total synthesis of (-)-scabronine G, an inducer of neurotrophic factor production. Keywords Mesh Terms:
KEYWORDS: Nerve Growth Factors
MESH TERMS: biosynthesis
Chemical & Substance for Abstract: Total synthesis of (-)-scabronine G, an inducer of neurotrophic factor production. Information
Substance Name: scabronine G
Registry Number: 0
Grant and Affiliation Information for Total synthesis of (-)-scabronine G, an inducer of neurotrophic factor production.
AFFILIATION: Laboratory for Bioorganic Chemistry and Laboratory of Biochemistry and Pharmacology, Sloan-Kettering Institute for Cancer Research, New York, New York 10021, USA.
Country: United States
AGENCY: United States NHLBI
GRANT: HL 25848
ACRONYM: HL
MEDLINETA: J Am Chem Soc
REFSOURCE:
DATABASENAME:
ACCESSION NUMBER:
Number Hits: 0
Total synthesis of --scabronine G, an inducer of neurotrophic factor production Related Publications