[Topical steroid injection for refractory oral chronic graft-versus-host disease]

[Topical steroid injection for refractory oral chronic graft-versus-host disease] Research Abstract Details 

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[Topical steroid injection for refractory oral chronic graft-versus-host disease] Abstract Text:

Yumiko Ohbayashi,Osamu Imataki,Ayuko Higuchi,Minoru Miyake,Yukiko Ohue,Hiroaki Ohnishi,Yumiko Ohbayashi,Osamu Imataki,Ayuko Higuchi,Minoru Miyake,Yukiko Ohue,Hiroaki Ohnishi,

The standard treatment for refractory oral chronic graft versus host disease (GVHD) has not been established. We present a case of AML accompanied by oral chronic GVHD in a 55-year-old man after allogeneic stem cell transplantation. The stomatitis of the patient was prolonged for a year and resistant to standard immunosuppressant therapy, including systemic administration of prednisolone and tacrolimus; however, local injection of 0.2% dexamethasone (0.5 mg per cm2) into the ulcerative area was drastically effective in improving refractory mucositis and mitigated a vicious cycle of mucosal damage and poor oral hygiene.

[Topical steroid injection for refractory oral chronic graft-versus-host disease] Publishing Authors By Initials

Y Ohbayashi,O Imataki,A Higuchi,M Miyake,Y Ohue,H Ohnishi,Y Ohbayashi,O Imataki,A Higuchi,M Miyake,Y Ohue,H Ohnishi,

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[Topical steroid injection for refractory oral chronic graft-versus-host disease] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: [Rinsh? ketsueki] The Japanese journal of clinical

VOLUME: 48

Page Numbers: 1508-10

Journal Abbreviation: Rinsho Ketsueki

ISSN: 0485-1439

DAY: 17

MONTH: Nov

YEAR: 2007

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LANGUAGE: jpn

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AFFILIATION: Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Kagawa University, Kagawa, Japan.

Country: Japan

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MEDLINETA: Rinsho Ketsueki

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