TIPS versus transcatheter sclerotherapy for gastric varices.

TIPS versus transcatheter sclerotherapy for gastric varices. Research Abstract Details 

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TIPS versus transcatheter sclerotherapy for gastric varices. Abstract Text:

Teruhisa Ninoi,Kenji Nakamura,Toshio Kaminou,Norifumi Nishida,Yukimasa Sakai,Toshiaki Kitayama,Masao Hamuro,Ryusaku Yamada,Tetsuo Arakawa,Yuichi Inoue,

OBJECTIVE: The purpose of our study was to compare the efficacy and long-term results of transjugular intrahepatic portosystemic shunt (TIPS) with those of transcatheter sclerotherapy for the treatment of gastric varices. MATERIALS AND METHODS: A total of 139 cirrhotic patients with gastric varices underwent endovascular treatment. Of the 139 patients, 104 without hepatocellular carcinoma were enrolled; 27 patients were treated with TIPS, and 77 patients with transcatheter sclerotherapy. Bleeding of gastric varices and survival rates were compared between the TIPS and transcatheter sclerotherapy groups. Multivariate analysis was used to identify the prognostic factors for gastric variceal bleeding and survival. Changes in liver function were evaluated in each group. RESULTS: The cumulative gastric variceal bleeding rate at 1 year was 20% in the TIPS group and 2% in the transcatheter sclerotherapy group (p < 0.01). The prognostic factor associated with gastric variceal bleeding was the treatment method. The cumulative survival rates at 1, 3, and 5 years were, respectively, 81%, 64%, and 40% in the TIPS group and 96%, 83%, and 76% in the transcatheter sclerotherapy group (p < 0.01). The prognostic factors for survival were the treatment method and the Child-Pugh classification of liver disease. For patients categorized in Child-Pugh class A, the survival rate was higher in the transcatheter sclerotherapy group than in the TIPS group (p < 0.01). For patients in Child-Pugh classes B and C, no significant difference was seen between the two groups. Liver function tended to improve in the transcatheter sclerotherapy group. CONCLUSION: Transcatheter sclerotherapy may provide better control of gastric variceal bleeding than TIPS. Transcatheter sclerotherapy may contribute to a higher survival rate than TIPS in patients with Child-Pugh class A disease.

TIPS versus transcatheter sclerotherapy for gastric varices. Publishing Authors By Initials

T Ninoi,K Nakamura,T Kaminou,N Nishida,Y Sakai,T Kitayama,M Hamuro,R Yamada,T Arakawa,Y Inoue,

For similar diagnosis: prognosis: treatment outcome research abstracts see: diagnosis: prognosis: treatment outcome research

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TIPS versus transcatheter sclerotherapy for gastric varices. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: AJR. American journal of roentgenology

VOLUME: 183

Page Numbers: 369-76

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ISSN: 0361-803X

DAY: 15

MONTH: Aug

YEAR: 2004

TIPS versus transcatheter sclerotherapy for gastric varices. Information

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LANGUAGE: eng

NlmUniqueID: 7708173

TIPS versus transcatheter sclerotherapy for gastric varices. Keywords Mesh Terms:

KEYWORDS: Treatment Outcome

MESH TERMS: therapy

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Grant and Affiliation Information for TIPS versus transcatheter sclerotherapy for gastric varices.

AFFILIATION: Department of Radiology, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka 545-8585, Japan. ninoi@msic.med.osaka-cu.ac.jp

Country: United States

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MEDLINETA: AJR Am J Roentgenol

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