Time-resolved diffuse optical tomography and its application to in vitro and in vivo imaging.

Time-resolved diffuse optical tomography and its application to in vitro and in vivo imaging. Research Abstract Details 

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Time-resolved diffuse optical tomography and its application to in vitro and in vivo imaging. Abstract Text:

Huijuan Zhao,Feng Gao,Yukari Tanikawa,Yukio Yamada,

This work reviews our research during the past several years on time-resolved (TR) near-infrared diffuse optical tomography (DOT). Following an introduction of the measuring modes, two proposed schemes of image reconstruction in TR-DOT are described: one utilizes the full TR data, and the other, referred to as the modified generalized pulse spectrum technique (GPST), uses the featured data extracted from the TR measurement. The performances of the two algorithms in quantitativeness and spatial resolution are comparatively investigated with 2-D simulated data. TR-DOT images are then presented for phantom experiments, which are obtained by using a 16-channel time-correlated single photon counting system, and the factors affecting the quantification of the reconstruction are discussed. Finally, in vitro and in vivo imaging examples are illustrated for validating the capibility of TR-DOT to provide not only the anatomical but also the physiological information of the objects.

Time-resolved diffuse optical tomography and its application to in vitro and in vivo imaging. Publishing Authors By Initials

H Zhao,F Gao,Y Tanikawa,Y Yamada,

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MEDLINE DATE: 2007 Nov-Dec

Time-resolved diffuse optical tomography and its application to in vitro and in vivo imaging. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of biomedical optics

VOLUME: 12

Page Numbers: 062107

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ISSN: 1083-3668

DAY: 31

MONTH: 12

YEAR: 2007

Time-resolved diffuse optical tomography and its application to in vitro and in vivo imaging. Information

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LANGUAGE: eng

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Grant and Affiliation Information for Time-resolved diffuse optical tomography and its application to in vitro and in vivo imaging.

AFFILIATION: Tianjin University, State Key Laboratory of Precision Measuring Technology and Instruments, Tianjin 3000072, China and Tianjin University, College of Precision Instrument and Optoelectronics Engineering, Tianjin 3000072, China.

Country: United States

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MEDLINETA: J Biomed Opt

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