Time and decision making: differential contribution of the posterior insular cortex and the striatum during a delay discounting task.

Time and decision making: differential contribution of the posterior insular cortex and the striatum during a delay discounting task. Research Abstract Details 

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Time and decision making: differential contribution of the posterior insular cortex and the striatum during a delay discounting task. Abstract Text:

Marc Wittmann,David S Leland,Martin P Paulus,Marc Wittmann,David S Leland,Martin P Paulus,

Delay discounting refers to the fact that an immediate reward is valued more than the same reward if it occurs some time in the future. To examine the neural substrates underlying this process, we studied 13 healthy volunteers who repeatedly had to decide between an immediate and parametrically varied delayed hypothetical reward using a delay discounting task during event-related functional magnetic resonance imaging. Subject's preference judgments resulted in different discounting slopes for shorter (<1 year) and for longer (> or =1 year) delays. Neural activation associated with the shorter delays relative to the longer delays was associated with increased activation in the head of the left caudate nucleus and putamen. When individuals selected the delayed relative to the immediate reward, a strong activation was found in bilateral posterior insular cortex. Several brain areas including the left caudate nucleus showed a correlation between the behaviorally determined discounting and brain activation for the contrast of intervals with delays <1 and > or =1 year. These results suggest that (1) the posterior insula, which is a critical component of the decision-making neural network, is involved in delaying gratification and (2) the degree of neural activation in the striatum, which plays a fundamental role in reward prediction and in time estimation, may code for the time delay.

Time and decision making: differential contribution of the posterior insular cortex and the striatum during a delay discounting task. Publishing Authors By Initials

M Wittmann,DS Leland,MP Paulus,M Wittmann,DS Leland,MP Paulus,

For similar psychological phenomena and processes: mental processes: perception: time perception research abstracts see: psychological phenomena and processes: mental processes: perception: time perception research

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Time and decision making: differential contribution of the posterior insular cortex and the striatum during a delay discounting task. Journal Published:

PUBLICATION TYPE: Research Support, U.S. Gov't,

Journal: Experimental brain research. Experimentelle Hirnf

VOLUME: 179

Page Numbers: 643-53

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ISSN: 0014-4819

DAY: 10

MONTH: 01

YEAR: 2007

Time and decision making: differential contribution of the posterior insular cortex and the striatum during a delay discounting task. Information

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LANGUAGE: eng

NlmUniqueID: 43312

Time and decision making: differential contribution of the posterior insular cortex and the striatum during a delay discounting task. Keywords Mesh Terms:

KEYWORDS: Time Perception

MESH TERMS: physiology

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Grant and Affiliation Information for Time and decision making: differential contribution of the posterior insular cortex and the striatum during a delay discounting task.

AFFILIATION: Department of Psychiatry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093-9116A, USA. wittmann@ucsd.edu

Country: Germany

AGENCY: United States NIDA

GRANT: R21DA13186

ACRONYM: DA

MEDLINETA: Exp Brain Res

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