Thyroid function in children with chronic renal failure. Abstract Text:
This study was undertaken to test the thyroid function in non-dialyzed children with chronic renal failure (CRF). Sixteen children with CRF and 12 healthy children who served as controls were studied for their thyroid function status. We found a significant increase in the serum thyroid stimulating hormone (TSH) level and a significant decrease in serum Triiodo thyronine (T3) levels in children with CRF as compared to the healthy children (p 0.2). There was a weak negative correlation between hemoglobin concentration and serum TSH (r = - 45) as well as between blood urea nitrogen and serum T3 (r= -0.30) in children with CRF. These results suggest that children with CRF commonly have a state of biochemical hypothyroidism although they are clinically euthyroid. Early renal transplantation is indicated to correct such metabolic defects.
Thyroid function in children with chronic renal failure. Publishing Authors By Initials