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[Therapy of viral hepatitis]

[Therapy of viral hepatitis] Research Abstract Details 

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  • [Therapy of viral hepatitis] Abstract Text:

    b burckhardtB Burckhardt,j reichenJ Reichen,

    Chronic viral hepatitis is a leading cause of chronic hepatitis, liver cirrhosis, hepatic decompensation and hepatocellular carcinoma worldwide. Here, we will briefly review common indications and current therapies for chronic hepatitis B and C and discuss practical aspects of these therapies. Current therapies for hepatitis C aim at viral eradication. With the introduction of pegylated interferon and ribavirin viral eradication is successful in about 55% of treated patients. The goal of therapy of HBe antigen positive chronic hepatitis B is seroconversion to anti-HBe which can be achieved with interferon alpha in 25-45% of patients. A loss of HBs can be achieved in approximately 10%. Responders proceed significantly less to cirrhosis or hepatocellular carcinoma. Anti-HBe positive patients can be treated with interferon alpha or lamivudine. The former requires longer treatment and the results are disappointing. Lamivudine is a promising agent in the treatment of chronic hepatitis B, but the success is hampered by a high relapse rate and the emergence of viral resistance.

    [Therapy of viral hepatitis] Publishing Authors By Initials

    b burckhardtB Burckhardt,j reichenJ Reichen,

    For similar investigative techniques: clinical laboratory techniques: microbiological techniques: viral load research abstracts see: investigative techniques: clinical laboratory techniques: microbiological techniques: viral load research

    PUBMED ID PMID:

    MEDLINE DATE:

    [Therapy of viral hepatitis] Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Therapeutische Umschau. Revue thérapeutique

    VOLUME: 60

    Page Numbers: 651-6

    Journal Abbreviation:

    ISSN: 0040-5930

    DAY: 12

    MONTH: Oct

    YEAR: 2003

    [Therapy of viral hepatitis] Information

    Number of References:

    LANGUAGE: ger

    NlmUniqueID: 407224

    [Therapy of viral hepatitis] Keywords Mesh Terms:

    KEYWORDS: Viral Load

    MESH TERMS: therapeutic use

    Chemical & Substance for Abstract: [Therapy of viral hepatitis] Information

    Substance Name: Interferon Alfa-2b

    Registry Number: 99210-65-8

    Grant and Affiliation Information for [Therapy of viral hepatitis]

    AFFILIATION: Institut für Klinische Pharmakologie, Universität Bern. beat.burckhardt@ikp.unibe.ch

    Country: Switzerland

    Switzerland Research PublicationSwitzerland Research Publication

    AGENCY:

    GRANT:

    ACRONYM:

    MEDLINETA: Ther Umsch

    REFSOURCE:

    DATABASENAME:

    ACCESSION NUMBER:

    Number Hits: 0

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