[The value of DNA flow cytometry in evaluation of proliferating activity of neoplasm cells in patients with laryngeal cancer]

[The value of DNA flow cytometry in evaluation of proliferating activity of neoplasm cells in patients with laryngeal cancer] Research Abstract Details 

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[The value of DNA flow cytometry in evaluation of proliferating activity of neoplasm cells in patients with laryngeal cancer] Abstract Text:

W Golusi?ski,Z Szmeja,A Krygier-Stoja?owska,W Biczysko,

A study of DNA ploidy was carried out including 84 cases of laryngeal squamous cell carcinoma. Material was fixed during 30 min in 3% paraformaldehyde and embedded in low-melting-point paraffin. The histologic studies were done for diagnosis and general view. Results were as follows. The highest percentage of cancers with DNA diploidy was found in well- and medium-differentiated tumors. Among well-differentiated carcinomas there were 18% diploid versus 5% polyploid tumors. In the medium-differentiated cancers there were 23.5% diploid, 6% polyploid, and 6% hyperdiploid tumors. The highest percentage of DNA hyperdiploidy and poliploido-aneuploidy was found in low-differentiated cancers. Additionally, tumor proliferative activity was evaluated in relation to the percentage of cells in phase S of cellular cycle. Special attention was paid to tumors which revealed the phenomenon of DNA poliploidy-aneuploidy beside DNA diploidy.

[The value of DNA flow cytometry in evaluation of proliferating activity of neoplasm cells in patients with laryngeal cancer] Publishing Authors By Initials

W Golusi?ski,Z Szmeja,A Krygier-Stoja?owska,W Biczysko,

For similar genetic phenomena: ploidies research abstracts see: genetic phenomena: ploidies research

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[The value of DNA flow cytometry in evaluation of proliferating activity of neoplasm cells in patients with laryngeal cancer] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Otolaryngologia polska. The Polish otolaryngology

VOLUME: 52

Page Numbers: 411-7

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ISSN: 0030-6657

DAY: 28

MONTH: 12

YEAR: 1998

[The value of DNA flow cytometry in evaluation of proliferating activity of neoplasm cells in patients with laryngeal cancer] Information

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LANGUAGE: pol

NlmUniqueID: 404453

[The value of DNA flow cytometry in evaluation of proliferating activity of neoplasm cells in patients with laryngeal cancer] Keywords Mesh Terms:

KEYWORDS: Ploidies

MESH TERMS: genetics

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Grant and Affiliation Information for [The value of DNA flow cytometry in evaluation of proliferating activity of neoplasm cells in patients with laryngeal cancer]

AFFILIATION: Katedra i Klinika Otolaryngologii AM w Poznaniu.

Country: POLAND

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MEDLINETA: Otolaryngol Pol

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