The utility of spirometry in diagnosing pulmonary restriction.

The utility of spirometry in diagnosing pulmonary restriction. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

The utility of spirometry in diagnosing pulmonary restriction. Abstract Text:

Saiprakash B Venkateshiah,Octavian C Ioachimescu,Kevin McCarthy,James K Stoller,

The aim of this retrospective study was to determine the utility of the spirometric measurements FVC, FEV(1), and FEV(1)/FVC in diagnosing pulmonary restriction. Spirometry and lung volume measurements performed on the same patient visit were analyzed. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of (1) FVC < lower limit of normal (LLN) (NHANES III reference values) and (2) FVC < LLN and FEV(1)/FVC >/= LLN were compared to diagnose restriction based on lung volume measurements. In all, 18,282 pulmonary function tests from 8,315 patients were analyzed. Twenty-six percent of the patients (n = 2,213) had restriction based on lung volume measurements. The sensitivity, specificity, PPV, and NPV of FVC < LLN to diagnose restriction based on lung volume measurement criteria were 88.6%, 56.8%, 39.9%, and 93.9%, respectively. The sensitivity, specificity, PPV, and NPV of FVC < LLN and FEV(1)/FVC >/= normal to diagnose restriction based on lung volume criteria were 72.4%, 87.1%, 64.4%, and 90.7%, respectively. Analysis of ROC curves showed that spirometric criteria based on FVC alone performed better (area under the curve = 0.817) than those based on the combined criteria of FVC and FEV(1)/FVC (area under the curve = 0.584). Consistent with earlier findings, the negative predictive value for a normal FVC (>/= LLN) to exclude pulmonary restriction was high in this series (up to 95.7%). Also, a spirometric diagnosis of "restriction" (FVC < LLN and FEV(1)/FVC >/= LLN) had a positive predictive value of 26.3-73.9%. On this basis, normal FVC can be regarded as excluding restriction with high reliability.

The utility of spirometry in diagnosing pulmonary restriction. Publishing Authors By Initials

SB Venkateshiah,OC Ioachimescu,K McCarthy,JK Stoller,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE: 2008 Jan-Feb

The utility of spirometry in diagnosing pulmonary restriction. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Lung

VOLUME: 186

Page Numbers: 19-25

Journal Abbreviation: Lung

ISSN: 0341-2040

DAY: 8

MONTH: 11

YEAR: 2007

The utility of spirometry in diagnosing pulmonary restriction. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 7701875

The utility of spirometry in diagnosing pulmonary restriction. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: The utility of spirometry in diagnosing pulmonary restriction. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for The utility of spirometry in diagnosing pulmonary restriction.

AFFILIATION: Department of Pulmonary, Critical Care and Sleep Medicine, Creighton University, 601 North 30th Street, Suite 3820, Omaha, Nebraska, 68131, USA, saiprakashv@creighton.edu.

Country: United States

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Lung

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

The utility of spirometry in diagnosing pulmonary restriction Related Publications

• A women with ulcerating, painful skin lesions.
• An analysis of needs for respiratory therapists in northeast ohio and development of strategies to meet increased recruitment demands.
• Antitrypsin deficiency vs Gianotti-Crosti syndrome.
• Association between Randall's plaque and calcifying nanoparticles.
• Changing paradigms in the surgical and medical management of acromegaly.
• Endoscopic management of obstructive complications in ureterosigmoidostomy.
• Exploring Leadership Competencies in Established and Aspiring Physician Leaders: An Interview-based Study.
• Isolated familial benign chronic pemphigus.
• Laboratory Evaluation of the Vortran Automatic Resuscitator Model RTM.
• Laparoscopic nephrectomy, ex vivo partial nephrectomy followed by allograft renal transplantation.
• Long-term outcomes and late complications of laparoscopic nephrectomy with renal autotransplantation.
• Modern trends in British psychiatry.
• Oral calcium supplementation associated with decreased likelihood of nephrolithiasis prior to surgery for hyperparathyroidism.
• Percutaneous management of stones in transplanted kidneys.
• Quality control for spirometry in large epidemiologic studies: "breathing quality" into our work.
• Social health and psychiatric service.
• Social work and the ex-serviceman; the psychiatric problem.
• Sphingosine-1-phosphate (S1P) is a novel fibrotic mediator in the eye.
• Symptomatic perirenal serous cysts of müllerian origin mimicking renal cysts on CT.
• The authors respond:.
• The utility of spirometry in diagnosing pulmonary restriction.
• Therapy for alpha(1)-Antitrypsin Deficiency: Pharmacology and Clinical Recommendations.
• Urinary citrate levels do not correlate with urinary pH in patients with urinary stone formation.
• Why we are not morally required to select the best children: a response to savulescu.
• [Not Available.]