The use of single fraction Leksell stereotactic radiosurgery in the treatment of uveal melanoma.

The use of single fraction Leksell stereotactic radiosurgery in the treatment of uveal melanoma. Research Abstract Details 

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The use of single fraction Leksell stereotactic radiosurgery in the treatment of uveal melanoma. Abstract Text:

Fourteen patients with posterior uveal melanomas were treated using single fraction stereotactic radiosurgery. In each case a dose of 70 Gy was administered to the periphery of the tumour. Regression of the tumour has been observed in 13 patients, whilst the lesion has remained unchanged in one patient. The visual acuity has deteriorated in all 14 patients. Significant radiation induced adverse reactions were noted in 13 patients and include; retinopathy, optic neuropathy, rubeosis iridis, and secondary glaucoma. Two patients have required enucleation because of intractable rubeotic glaucoma. One patient has died from proven metastases. Although stereotactic radiosurgery appears to be a practical and effective method of treating uveal melanomas, its usefulness is limited by a high incidence of radiation induced adverse reactions. Further work is required to refine the current treatment protocol and establish an optimal prescription dose.

The use of single fraction Leksell stereotactic radiosurgery in the treatment of uveal melanoma. Publishing Authors By Initials

For similar visual acuity research abstracts see: visual acuity research

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The use of single fraction Leksell stereotactic radiosurgery in the treatment of uveal melanoma. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Acta ophthalmologica Scandinavica

VOLUME: 74

Page Numbers: 558-62

Journal Abbreviation: Acta Ophthalmol Scand

ISSN: 1395-3907

DAY: 17

MONTH: Dec

YEAR: 1996

The use of single fraction Leksell stereotactic radiosurgery in the treatment of uveal melanoma. Information

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LANGUAGE: eng

NlmUniqueID: 9507578

The use of single fraction Leksell stereotactic radiosurgery in the treatment of uveal melanoma. Keywords Mesh Terms:

KEYWORDS: Visual Acuity

MESH TERMS: surgery

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Grant and Affiliation Information for The use of single fraction Leksell stereotactic radiosurgery in the treatment of uveal melanoma.

AFFILIATION: Department of Ophthalmology and Orthoptics, University of Sheffield, UK.

Country: DENMARK

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MEDLINETA: Acta Ophthalmol Scand

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