The use of enoxaparin to prevent venous thromboembolism in patients undergoing radical retropubic prostatectomy: feasibility and utility.

The use of enoxaparin to prevent venous thromboembolism in patients undergoing radical retropubic prostatectomy: feasibility and utility. Research Abstract Details 

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The use of enoxaparin to prevent venous thromboembolism in patients undergoing radical retropubic prostatectomy: feasibility and utility. Abstract Text:

Kogenta Nakamura,Ali Kasraeian,Saif Yacoub,John Pendleton,Satoshi Anai,Charles J Rosser,Kogenta Nakamura,Ali Kasraeian,Saif Yacoub,John Pendleton,Satoshi Anai,Charles J Rosser,

OBJECTIVE: To assess the utility of enoxaparin in prevention of venous thromboembolism (VTE) in men poorly compliant with pneumatic compression stockings (PCS) in the immediate postoperative period after a radical retropubic prostatectomy (RP). MATERIALS AND METHODS: This retrospective study included 47 men who underwent RP at an inner-city tertiary care hospital. All patients were started on enoxaparin 40 mg subcutaneously 6-8 hours postoperatively and daily while hospitalized. Preoperative, operative, and postoperative data were collected and analyzed. Median follow-up was 18 months. RESULTS: Median patient age was 64 +/- 7 years, median prostate-specific antigen level was 4.9 ng/mL and median prostate biopsy-determined Gleason score was 6. Forty-one men (87%) underwent a pelvic lymph node dissection. Median operative time was 181 minutes (range 164-450 minutes). Median estimated blood loss was 700 mL. Approximately 36% of the men wore PCS the recommended > 19 hours/day. On average PCS were worn 10.3 +/- 7.5 hours/day. Postoperative complications were not increased in this cohort. Two patients developed pulmonary embolism requiring long-term anticoagulation. There were no mortalities. CONCLUSIONS: In men non-compliant with PCS, initiation of enoxaparin in the immediate postoperative setting was well-tolerated and maintained a low (4%) rate of VTE. Thus, enoxaparin may be useful in adjunct with PCS in these patients.

The use of enoxaparin to prevent venous thromboembolism in patients undergoing radical retropubic prostatectomy: feasibility and utility. Publishing Authors By Initials

K Nakamura,A Kasraeian,S Yacoub,J Pendleton,S Anai,CJ Rosser,K Nakamura,A Kasraeian,S Yacoub,J Pendleton,S Anai,CJ Rosser,

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The use of enoxaparin to prevent venous thromboembolism in patients undergoing radical retropubic prostatectomy: feasibility and utility. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: International braz j urol : official journal of th

VOLUME: 33

Page Numbers: 347-52; discussion 352-4

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ISSN: 1677-5538

DAY: 13

MONTH: 07

YEAR: 2007

The use of enoxaparin to prevent venous thromboembolism in patients undergoing radical retropubic prostatectomy: feasibility and utility. Information

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LANGUAGE: eng

NlmUniqueID: 101158091

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Grant and Affiliation Information for The use of enoxaparin to prevent venous thromboembolism in patients undergoing radical retropubic prostatectomy: feasibility and utility.

AFFILIATION: Division of Urology, University of Florida, Jacksonville, Florida, USA.

Country: Brazil

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MEDLINETA: Int Braz J Urol

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