The treatment of movement disorders by deep brain stimulation.

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The treatment of movement disorders by deep brain stimulation. Abstract Text:

Hong Yu,Joseph S Neimat,Hong Yu,Joseph S Neimat,Hong Yu,Joseph S Neimat,

It has been understood, for some time, that modulation of deep brain nuclei within the basal ganglia and thalamus can have a therapeutic effect in patients with movement disorders. Because of its reversibility and adjustability, deep brain stimulation (DBS) has largely come to replace traditional ablation procedures. The clinical effects of DBS vary, depending both on the target being stimulated and on the parameters of stimulation. Both aspects are currently the subject of substantial research and discovery. The most common targets for DBS treatment include the subthalamic nucleus for the treatment of advanced Parkinson's disease, the ventral intermediate nucleus of the thalamus for the treatment of medically refractory essential tremor, and the globus pallidus interna for the treatment of both cervical and generalized dystonias and Parkinson's disease. We review the current indications, targets, outcomes, and general procedure of DBS for essential tremor, Parkinson's disease, and dystonia.

The treatment of movement disorders by deep brain stimulation. Publishing Authors By Initials

H Yu,JS Neimat,H Yu,JS Neimat,H Yu,JS Neimat,

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The treatment of movement disorders by deep brain stimulation. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Neurotherapeutics : the journal of the American So

VOLUME: 5

Page Numbers: 26-36

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ISSN: 1933-7213

DAY: 31

MONTH: Jan

YEAR: 2008

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LANGUAGE: eng

NlmUniqueID: 101290381

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AFFILIATION: Department of Neurological Surgery, Vanderbilt University, Nashville, Tennessee 37232.

Country: United States

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MEDLINETA: Neurotherapeutics

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